DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a8 and CYP735A2

DIOPT Version :9

Sequence 1:	NP_523749.2	Gene:	Cyp6a8 / 36666	FlyBaseID:	FBgn0013772	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_176882.1	Gene:	CYP735A2 / 843031	AraportID:	AT1G67110	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	524	Identity:	141/524 - (26%)
Similarity:	221/524 - (42%)	Gaps:	95/524 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALTYILFQVAVALLAIL-----TYYI--HRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEI 58
            :.|.|:|..|...:|.:|     .|::  .|...:.:|:||....|.|:.||:.::.|..: |..
plant     5 LVLKYVLVIVMTLILRVLYDSICCYFLTPRRIKKFMERQGITGPKPRLLTGNIIDISKMLS-HSA 68

  Fly    59 FQD----HYNKFRESKAPFVG--------FFFFQ--SPAAFVIDLELAKQILIKD--------FS 101
            ..|    |:|........:|.        |..:.  .|...:.:.|:.|::|.|.        ..
plant    69 SNDCSSIHHNIVPRLLPHYVSWSKQYGKRFIMWNGTEPRLCLTETEMIKELLTKHNPVTGKSWLQ 133

  Fly   102 NFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEK 166
            ....||.        |...|...:|..|...|:..:..||..::|.....:|    |...:|.|:
plant   134 QQGTKGF--------IGRGLLMANGEAWHHQRHMAAPAFTRDRLKGYAKHMV----ECTKMMAER 186

  Fly   167 VPK--NSVLEIRDLVARFTVDVIGTCAFGIQCNSLRD-------------EKAEFLYF-GKRSLV 215
            :.|  ...:||.:.:.|.|.|:|....||..|:..::             :....|.| |.|.|.
plant   187 LRKEVGEEVEIGEEMRRLTADIISRTEFGSSCDKGKELFSLLTVLQRLCAQATRHLCFPGSRFLP 251

  Fly   216 DKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIVTETVAVR-EKEHIKRNDFM--DMLIE 277
            .|.:               |::..::|.      ..|::.|.:..| :...|.|:...  |:|..
plant   252 SKYN---------------REIKSLKTE------VERLLMEIIDSRKDSVEIGRSSSYGDDLLGL 295

  Fly   278 LKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEE 342
            |.||.:....|      |.::.::.:...||..|.||:|..:.:.|..||.||..||.||.||.:
plant   296 LLNQMDSNKNN------LNVQMIMDECKTFFFTGHETTSLLLTWTLMLLAHNPTWQDNVRDEVRQ 354

  Fly   343 VIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPS 407
            |..| |...:.|....|..||:|::|:||||.....|.|||.:...:   .:.:|..|.|:.||.
plant   355 VCGQ-DGVPSVEQLSSLTSLNKVINESLRLYPPATLLPRMAFEDIKL---GDLIIPKGLSIWIPV 415

  Fly   408 SAIHHDPSIYPEPF-EFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRN 471
            .||||...::.|.. ||.||||:....|.  |..::||..|||||||..|..|:|:|.||:|:..
plant   416 LAIHHSNELWGEDANEFNPERFTTRSFAS--SRHFMPFAAGPRNCIGQTFAMMEAKIILAMLVSK 478

  Fly   472 FKFS 475
            |.|:
plant   479 FSFA 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	130/479 (27%)
CYP735A2	NP_176882.1	PLN02290	2..511	CDD:215164	141/524 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910