DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a8 and CYP705A4

DIOPT Version :9

Sequence 1:	NP_523749.2	Gene:	Cyp6a8 / 36666	FlyBaseID:	FBgn0013772	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_193273.1	Gene:	CYP705A4 / 827204	AraportID:	AT4G15380	Length:	517	Species:	Arabidopsis thaliana

Alignment Length:	530	Identity:	114/530 - (21%)
Similarity:	198/530 - (37%)	Gaps:	100/530 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ALTYILFQVAVALLAILTY----YIHRKLTYFKRR-------GIPFVAPHL-IRGNMEELQKTKN 54
            |:..|.||.....:.:..:    |.|    :||:.       .:|...|.| |.|::..|....
plant     3 AMNMIDFQNCFIFILLCLFSRLCYSH----FFKKPKDPRLHFDLPPSPPSLPIIGHLHLLLSVL- 62

  Fly    55 IHEIFQDHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISA 119
            :|...|....|:    ...:....|:.|...:....:|.:|......|.|.:|  :...||.:.|
plant    63 LHRSLQKLSTKY----GSILYLRVFRFPVVLISSASIAYEIFRAHDLNISYRG--FTPTDDSLFA 121

  Fly   120 HLFNL----DGAQWRLLRNKL-SSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLV 179
            ..|:.    .|..|:.::..| ::.|.....:........|...|...:.:|..|...:||....
plant   122 GSFSFISAPYGDYWKFMKKVLVTNVFGPQAHEQSRGVRADVLERFYGNLFDKAIKKQSVEICAEA 186

  Fly   180 ARFTVDVIGTCAFGIQCNSLR--------DEKAEFLYFG-------KRSLVD--KRHGTLLNGFM 227
            .:.:...|.....|..|:..|        |...:.|:|.       |:.:|.  |:..|::
plant   187 LKLSNSSICKMIMGRSCSEERFRALATELDVLTKKLFFANMLRAWFKKLVVSLFKKETTVI---- 247

  Fly   228 RSYPKLARKLGMVRTAPHIQEFYSRIVTETVAVREKE---HIKRNDFMDMLIELKNQKEMTLENG 289
             ||              ...|....|:.|    .||:   |.:|.|.||.|:.....     ||.
plant   248 -SY--------------RFDELLESILVE----HEKKLDVHHQRTDLMDALLAAYRD-----ENA 288

  Fly   290 DVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEV------IEQHD 348
            :.  .:|...:.:.......||.|....|:.:|:.|:..||::.:::|.|::.|      |::.|
plant   289 EY--KITRNHIKSIIADLLFAGTENQVQTIQWAMAEIINNPNVLERLRGEIDSVVGKSRLIQETD 351

  Fly   349 QNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHD 413
                   ...|.||..|:.||:||:...|...|...:...:.|   |.:....||::...|:..|
plant   352 -------LPKLPYLQAVVKETIRLHPPGPFFLRFTKEGCRIRG---FYVPENTSVVVNVYAVMRD 406

  Fly   414 PSIYPEPFEFRPERF------SPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNF 472
            |..:.:|..|:||||      ..||......:.:||||.|.|:|.|.....:.....:.::::.|
plant   407 PDAWEDPLVFKPERFLASSRAEQEEERREKEIKYLPFGSGRRSCPGENLAYVIMGTAIGVMVQGF 471

  Fly   473 KFSTCSKTPN 482
            ::.|..:..|
plant   472 EWRTTEEKIN 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	105/482 (22%)
CYP705A4	NP_193273.1	p450	70..508	CDD:386267	98/458 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010