Protein Alignment Cyp6a8 and cyp26b1

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001072655.1
• Gene: cyp26b1 / 780112
• XenbaseID: XB-GENE-991500
• Length: 511
• Species: Xenopus tropicalis
• Alignment Length: 508
• Identity: 112/508 - (22%)
• Similarity: 200/508 - (39%)
• Gaps: 78/508 - (15%)

  Fly    10 VAVALLAILT---YYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFRESKA 71
            |:||||..::   :.:....|..|...:|     :.:|:|......:..|.|.|.  :.|:.|:.
 Frog    20 VSVALLLAVSQQLWQLRWAATRDKSCKLP-----IPKGSMGFPLVGETFHWILQG--SDFQSSRR 77

  Fly    72 PFVGFFF----FQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAH-------LFNLD 125
            ...|..|    ...|...|...|..::||:.:....|.:.        |.|..       |.|..
 Frog    78 EKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEW--------PRSTRMLLGPNSLANSI 134

  Fly   126 GAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK--NSVLEIRDLVARFTVDVIG 188
            |...|..|...|..|:...::...|.:..|..:.:.|.... |:  |...|.:.|..|..:.|:
 Frog   135 GDIHRHKRKVFSKIFSHEALESYLPKIQLVIQDTLRVWSSN-PESINVYCEAQKLTFRMAIRVL- 197

  Fly   189 TCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRI 253
               .|.:   |.||:...|:...:..|:......::.....|.:..|...|:            :
 Frog   198 ---LGFR---LSDEELSQLFQVFQQFVENVFSLPVDVPFSGYRRGIRAREML------------L 244

  Fly   254 VTETVAVREK-EHIKRNDFMDMLIELKNQKEMTLENG-DVVRGLTMEEVLAQAFVFFIAGFETSS 316
            .:...|::|| ::.:..|:.|.|       ::.:|:| :..:.|||:|:.........|.:.|::
 Frog   245 KSLEKAIQEKLQNTQGKDYADAL-------DILIESGKEHGKELTMQELKDGTLELIFAAYATTA 302

  Fly   317 STMGFALYELAKNPDIQDKVRAEVEEVIEQH-----DQNFTYECTKDLKYLNQVLDETLRLYTIV 376
            |.....:.:|.|:|.:.:|:|.|:......|     :.....|....|.||:.|:.|.|||::.|
 Frog   303 SASTSLIMQLLKHPSVLEKLREELRGNSILHNGCVCEGALRVETISSLHYLDCVIKEILRLFSPV 367

  Fly   377 PNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFS---PEESAGRPS 438
            ....|...:.:.:.|   |.|..|.||:......|....::.:...|.|:||.   .|:..||
 Frog   368 SGGYRTVLQTFELDG---FQIPKGWSVLYSIRDTHDTAPVFKDVDVFDPDRFGQDRTEDKDGR-- 427

  Fly   439 VAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKT-----PNPLVY 486
            ..:||||.|.|||:|....::..::....|....:|...::|     |.|:|:
 Frog   428 FHYLPFGGGVRNCLGKHLAKLFLKVLAIELASMSRFELATRTFPKIMPVPVVH 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	97/445 (22%)
cyp26b1	NP_001072655.1	CYP26B1	60..489	CDD:410730	102/463 (22%)