Protein Alignment Cyp6a8 and Cyp4f18

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_077764.2
• Gene: Cyp4f18 / 72054
• MGIID: 1919304
• Length: 524
• Species: Mus musculus
• Alignment Length: 501
• Identity: 121/501 - (24%)
• Similarity: 219/501 - (43%)
• Gaps: 86/501 - (17%)

  Fly    41 LIRGNMEELQKTKNIHEIFQDHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILI-KDFSNFS 104
            ||:.:.|.|...:::...|:|....:.....|.:..|.    .||:..:.||..::. ||
Mouse    66 LIQSSEEGLLYIQSLVRTFRDACCWWVGPLHPVIRIFH----PAFIKPVVLAPALVAPKD----- 121

  Fly   105 NKGIFYNEKDDPISAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK 169
              .:||......:...|....|.:|...|..|:..|....:|    ..|.|.|:...:||.|..:
Mouse   122 --TVFYRFLKPWLGDGLLMSTGDKWSRHRRMLTPAFHFNILK----PYVKVFNDSTNIMHAKWQR 180

  Fly   170 -----NSVLEIRDLVARFTVDVIGTCAFGIQCNSLRDEKAEFL--YFGKRSLVDKRHGTLL---- 223
                 ::.|.:.:.::..|:|.:..|.|....| .:::.:|::  .....:||.:||..||
Mouse   181 LASKGSAYLNMFEHISLMTLDSLQKCVFSFDSN-CQEKPSEYITAILELSTLVARRHQRLLLHVD 244

  Fly   224 ------NGFMRSYPKLARKLGMVRTAPHIQEFYSRIVTE----------TVAVREKEHIKRNDFM 272
                  :..|| :.|..|.         :.:|...::.|          ...::.|...|..||:
Mouse   245 LFYYLTHDGMR-FRKACRL---------VHDFTDAVIRERRRTLLDQGGVDVLKAKAKAKTLDFI 299

  Fly   273 DMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVR 337
            |:|:..|:      |:|   :.|:.|::.|:|..|...|.:|::|.:.:.||.||::|:.|::.|
Mouse   300 DVLLLSKD------EHG---KALSDEDIRAEADTFMFGGHDTTASGLSWILYNLARHPEYQERCR 355

  Fly   338 AEVEEVI-EQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQ 401
            .||.|:: ::..:...::....|.:|...:.|:|||:..|..:.|...:..|:|          .
Mouse   356 QEVRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPVTAISRCCTQDIVLP----------D 410

  Fly   402 SVIIPSSAI--------HHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQ 458
            ..:||...|        ||:|:::|:|..:.|.||..:...||..:|::||..|||||||..|..
Mouse   411 GRVIPKGVISRISIFGTHHNPAVWPDPEVYDPFRFDADNVKGRSPLAFIPFSAGPRNCIGQTFAM 475

  Fly   459 MQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLKVE 504
            .:.::.|||.:..|:.....|.|.    .....:|..:.|::||||
Mouse   476 SEMKVALALTLLRFRVLPDDKEPR----RKPELILRAEGGLWLKVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	118/498 (24%)
Cyp4f18	NP_077764.2	p450	52..516	CDD:365848	118/498 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900