Protein Alignment Cyp6a8 and Cyp4f14

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001191262.1
• Gene: Cyp4f14 / 64385
• MGIID: 1927669
• Length: 524
• Species: Mus musculus
• Alignment Length: 458
• Identity: 118/458 - (25%)
• Similarity: 210/458 - (45%)
• Gaps: 55/458 - (12%)

  Fly    75 GFFFFQSPAAFVIDL---ELAKQIL-------IKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQW 129
            ||..:..|...||.|   ::.:.||       :||.       |||:.....:...|....|.:|
Mouse    87 GFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDV-------IFYSILKPWLGDGLLVSAGDKW 144

  Fly   130 RLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK-----NSVLEIRDLVARFTVDVIGT 189
            ...|..|:..|....:|    ..|.:.|:...:||.|..:     ::.|::.:.|:..|:|.:..
Mouse   145 SRHRRMLTPAFHFNILK----PYVKIFNDSTNIMHAKWQRLISDGSARLDMFEHVSLMTLDSLQK 205

  Fly   190 CAFGIQCNSLRDEKAEFL--YFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSR 252
            |.|....| .:::.:|::  .....:||.|||...|......|......:...:....:.||...
Mouse   206 CVFSFDSN-CQEKSSEYIAAILELSALVAKRHQQPLMFMDLLYNLTPDGMRFRKACNVVHEFTDA 269

  Fly   253 IVTE---TVA-------VREKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVF 307
            ::.|   |:.       ::.|...|..||:|:|:..|:      |:|   :.|:.|::.|:|..|
Mouse   270 VIRERHRTLPDQGLDDFLKSKAKSKTLDFIDVLLLSKD------EDG---KELSDEDIRAEADTF 325

  Fly   308 FIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIE-QHDQNFTYECTKDLKYLNQVLDETLR 371
            ...|.:|::|.:.:.||.||::|:.|::.|.||:|::. :..:...::....|.:|...:.|:||
Mouse   326 MFEGHDTTASGLSWILYNLARHPEYQERCRQEVQELLRGREPEEIEWDDLAQLPFLTMCIKESLR 390

  Fly   372 LYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGR 436
            |:..|..:.|...:..::|  ....|..|...:|....|||:||::|:|..:.|.||.||.....
Mouse   391 LHPPVTVISRCCTQDILLP--DGRTIPKGIICLISIFGIHHNPSVWPDPEVYDPFRFDPENIKDS 453

  Fly   437 PSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYL 501
            ..:|::||..|||||||..|...:.::.|||.:..|:.....|.|.   ..|: .:|..:.|::|
Mouse   454 SPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDDKEPR---RQPE-LILRAEGGLWL 514

  Fly   502 KVE 504
            :||
Mouse   515 RVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	116/455 (25%)
Cyp4f14	NP_001191262.1	p450	52..511	CDD:365848	114/450 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900