Protein Alignment Cyp6a8 and Cyp4f40

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_006524820.1
• Gene: Cyp4f40 / 631304
• MGIID: 3645508
• Length: 551
• Species: Mus musculus
• Alignment Length: 461
• Identity: 113/461 - (24%)
• Similarity: 204/461 - (44%)
• Gaps: 61/461 - (13%)

  Fly    75 GFFFFQSPAAFVIDL---ELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRNKL 136
            ||..:..|...:|.|   ::.:.:|....:......|||:.....:...|....|.:|...|..|
Mouse   114 GFMTWLGPIVPLITLCHPDIIRSVLSASAAVAPKDDIFYSFLKPWLGDGLLVSAGDKWNRHRRML 178

  Fly   137 SSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK-----NSVLEIRDLVARFTVDVIGTCAFGIQC 196
            :..|....:|    ..|.:.|:...:||.|..:     ::.|.:.:.::..|:|.:..|.|....
Mouse   179 TPAFHFNILK----PYVKIFNDSTNIMHAKWLRLASGGSTRLNMFENISLMTLDTLQKCVFSFNS 239

  Fly   197 NSLRDEKAEFL--YFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYS--RIV--- 254
            | .:::.::::  .....:|..||:..||......|          |..|....||.  |:|
Mouse   240 N-CQEKPSQYIAAILELSTLAVKRNEQLLMHVDLLY----------RLTPDGMRFYKACRLVHDF 293

  Fly   255 TETV---------------AVREKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQA 304
            |:.|               .::.|...|..||:|:|:..|:      |:|   :.|:.|::.|:|
Mouse   294 TDAVIQERRRTLLKHGGDDIIKAKAKSKTLDFIDVLLLTKD------EDG---KELSDEDIRAEA 349

  Fly   305 FVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHD-QNFTYECTKDLKYLNQVLDE 368
            ..|...|.:|::|.:.:.||.||::|:.|::.|.||:|::...| :...::....|.:|...:.|
Mouse   350 DTFMFRGHDTTASGLSWILYNLARHPEHQERCRQEVQELLRDRDPKEIEWDDLAQLPFLTMCIKE 414

  Fly   369 TLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEES 433
            :|||:..|..:.|...:...:|  ...:|..|...||.....||:|:::.:|..:.|.||.||..
Mouse   415 SLRLHPPVTMVSRCCTQDISLP--DGRIIPKGVICIINIFGTHHNPTVWRDPEVYDPFRFDPENI 477

  Fly   434 AGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDG 498
            ..|..::::||..|||||||..|...:.::.|||.:..|:.....|.|.    .....:|..:.|
Mouse   478 QARSPLSFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRILPDDKEPR----RKPELILRAEGG 538

  Fly   499 IYLKVE 504
            ::|:||
Mouse   539 LWLRVE 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	110/455 (24%)
Cyp4f40	XP_006524820.1	CYP4F	101..542	CDD:410772	110/457 (24%)