Protein Alignment Cyp6a8 and Cyp4f1

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_062569.2
• Gene: Cyp4f1 / 56266
• RGDID: 70926
• Length: 524
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 139/545 - (25%)
• Similarity: 235/545 - (43%)
• Gaps: 92/545 - (16%)

  Fly     4 TYILFQVAVALLAILT--YYIHRKLTYFKR-RGIP-------------FVAPHLIRGNMEELQKT 52
            |.:||..:..|..|||  |..:|.   |:| ||.|             .|.|  ....::||.:.
  Rat    21 TLLLFGASWILAQILTQIYAAYRN---FRRLRGFPQPPKRNWLMGHVGMVTP--TEQGLKELTRL 80

  Fly    53 KNIHEIFQDHYNKFRESKAPFVGFFFFQSPAAFVIDL---ELAKQIL-------IKDFSNFSNKG 107
            ...:.                .||..:..|...||.|   ::.:.||       :||.
  Rat    81 VGTYP----------------QGFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDV------- 122

  Fly   108 IFYNEKDDPISAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK--- 169
            |||......:...|....|.:|...|..|:..|....:|    ..|.:.|:...:||.|..:
  Rat   123 IFYTILKPWLGDGLLVSAGDKWSRHRRMLTPAFHFNILK----PYVKIFNDSTNIMHAKWKRLIS 183

  Fly   170 --NSVLEIRDLVARFTVDVIGTCAFGIQCNSLRDEKAEFL--YFGKRSLVDKRHGTLLNGFMRSY 230
              :|.|::.:.|:..|:|.:..|.|....| .:::.:|::  .....:||.|||...|......|
  Rat   184 EGSSRLDMFEHVSLMTLDSLQKCVFSFDSN-CQEKSSEYIAAILELSALVAKRHQQPLLFMDLLY 247

  Fly   231 PKLARKLGMVRTAPHIQEFYSRIVTE---TVA-------VREKEHIKRNDFMDMLIELKNQKEMT 285
            ......:...:....:.||...::.|   |:.       ::.|...|..||:|:|:..|:
  Rat   248 NLTPDGMRFHKACNLVHEFTDAVIRERRRTLPDQGLDEFLKSKAKSKTLDFIDVLLLTKD----- 307

  Fly   286 LENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHD-Q 349
             |:|   :.|:.|::.|:|..|...|.:|::|.:.:.||.|||:|:.|::.|.||:|::...| :
  Rat   308 -EDG---KELSDEDIRAEADTFMFEGHDTTASGLSWILYNLAKHPEYQERCRQEVQELLRDRDPE 368

  Fly   350 NFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDP 414
            ...::....|.:|...:.|:|||:..|..:.|...:..::|  ....|..|...:|....|||:|
  Rat   369 EIEWDDLAQLPFLTMCIKESLRLHPPVTVISRCCTQDILLP--DGRTIPKGIICLISIFGIHHNP 431

  Fly   415 SIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSK 479
            |::|:|..:.|.||.||.......:|::||..|||||||..|...:.::.|||.:..|:.....|
  Rat   432 SVWPDPEVYNPFRFDPENIKDSSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRLLPDDK 496

  Fly   480 TPNPLVYDPKSFVLGVKDGIYLKVE 504
            .|.   ..|: .:|..:.|::|:||
  Rat   497 EPR---RQPE-LILRAEGGLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	118/457 (26%)
Cyp4f1	NP_062569.2	CYP4F	74..515	CDD:410772	120/483 (25%)