Protein Alignment Cyp6a8 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001025122.2
• Gene: cyp26c1 / 554036
• ZFINID: ZDB-GENE-050714-2
• Length: 554
• Species: Danio rerio
• Alignment Length: 561
• Identity: 110/561 - (19%)
• Similarity: 187/561 - (33%)
• Gaps: 165/561 - (29%)

  Fly     3 LTYILFQVAVALL-AILTYYIHRKLTYFK----------------RRGIPFVAP--H-LIRGNME 47
            |...|..||.|:| .:|...:.|.|..|:                ..|.|.|..  | |.:|:..
Zfish     8 LVSALLSVADAVLPTVLLLAVSRLLWEFRWSITRDRTCKLPLPQGSMGWPLVGETFHWLFQGSSF 72

  Fly    48 ELQKTKNIHEIFQDHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNE 112
            .:.:.:...::|:.|               ....|...|...|..::||:.:.:....:.
Zfish    73 HISRREKHGKVFKTH---------------LLGKPLIRVTGAENIRKILLGEHTVVCTQW----- 117

  Fly   113 KDDPISAH-------LFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK- 169
               |.|..       |.|..|...:..|..|:..|:.|.::       :.......|:..::.|
Zfish   118 ---PQSTRIILGPNTLVNSVGDLHKRKRKVLAKVFSRGALE-------AYLTRLQDVVKSEIAKW 172

  Fly   170 ---NSVLEI----RDLVARFTVDVIGTCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFM 227
               ...:|:    :.|..|..|.|:    .|:.   |.:::..:|        .|....|:|...
Zfish   173 CTETGSVEVYTAAKSLTFRIAVRVL----LGLH---LEEQQITYL--------SKTFEQLMNNLF 222

  Fly   228 RSYPKLARKLGM---VRTAPHIQEFYSRIVTETVAVRE-KEHIKRNDFMDMLIELKNQKEMTLEN 288
             |.|......|:   :|....:.....:|:.|.:..:: .::....|:|     |.:.:|...|
Zfish   223 -SLPIDTPVSGLRKGIRAREILHSAMEKIIEEKLKKQQASDYCDAFDYM-----LSSARENDYE- 280

  Fly   289 GDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVE------------ 341
                  |||:|:...|.....|...|::|.....:.:|.::||:.::.|||:|
Zfish   281 ------LTMQELKETAVELIFAAHSTTASASTSLIMQLLRHPDVSERARAELESEGLITDGHGHC 339

  Fly   342 -------------EVIEQ----------------------------HDQNFTYECTKDLKYLNQV 365
                         |..|:                            |....:.|....|.||:.|
Zfish   340 RSRCNGNAISEEGEAAEKSTSDRRSAINKATYFEAGDKEEGRRSRTHVPYLSLEKLSQLSYLDCV 404

  Fly   366 LDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERF-- 428
            :.|.||....|....|...:.:.:.|   :.|..|.||:......|.....|..|..|.|:||
Zfish   405 VKEVLRFLPPVSGGYRTVLQTFELNG---YQIPKGWSVMYSIRDTHETAEAYQNPELFDPDRFCV 466

  Fly   429 SPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLI 469
            ..|||... ..:::|||.|.|.|||..         |||::
Zfish   467 GREESKSE-RFSYVPFGGGVRRCIGRE---------LALIV 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	92/474 (19%)
cyp26c1	NP_001025122.2	cytochrome_P450	59..537	CDD:477761	98/510 (19%)