Protein Alignment Cyp6a8 and Cyp3a41a

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_059092.2
• Gene: Cyp3a41a / 53973
• MGIID: 1858451
• Length: 504
• Species: Mus musculus
• Alignment Length: 519
• Identity: 165/519 - (31%)
• Similarity: 263/519 - (50%)
• Gaps: 62/519 - (11%)

  Fly    10 VAVALLAILTY-YIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFRESKAPF 73
            |.:|::.:|.| |..|....||::|||...|....|.:  |...|.:.:...:.|.|:.::
Mouse    13 VLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTV--LNYYKGLWKFDMECYEKYGKT---- 71

  Fly    74 VGFFFFQSPAAFVIDLELAKQILIKD-FSNFSNK------GIFYN----EKDDPISAHLFNLDGA 127
            .|.|..|.|...:.|.|:.|.:|:|: ||.|:|:      ||...    .||:
Mouse    72 WGLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAISISKDE------------ 124

  Fly   128 QWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVIGTCAF 192
            :|:..|..||.||||||:|.|:|.:....:..:..:.::..|...:.::|::..:::|||.:.:|
Mouse   125 EWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYSIDVITSTSF 189

  Fly   193 GIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRS-------YPKLARKLGMVRTAPHIQ--- 247
            |:..:||.:.:..|        |:|..|.|...|...       :|.|.....|:......:
Mouse   190 GVNVDSLNNPEDPF--------VEKAKGILRVDFFDPLVFSVVLFPFLTPVYEMLNICMFPKDSI 246

  Fly   248 EFYSRIVTETVAVR---EKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFI 309
            ||:.:.|......|   :::|  |.||:.:::...|..    ::.|..:.|:..|:.||:.||..
Mouse   247 EFFKKFVNRMKESRLDSKQKH--RVDFLQLMMNAHNNS----KDKDSHKALSDMEITAQSIVFIF 305

  Fly   310 AGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYT 374
            ||:||:|||:.|.||.||.:||||.|::.|::|.:...... ||:...:::||:.||:||||||.
Mouse   306 AGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETLPNKAPP-TYDTVMEMEYLDMVLNETLRLYP 369

  Fly   375 IVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSV 439
            |...|:|...|...:.|   ..|..|.:|:|||.|:||||..:|||.||:|||||.|........
Mouse   370 IGNRLERFCKKDVELNG---VYIPKGSTVMIPSYALHHDPQHWPEPEEFQPERFSKENKGSIDPY 431

  Fly   440 AWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLKV 503
            .::|||.|||||||:||..|..::.|..:::||.|..|.:|..||... :..:|..:..|.|||
Mouse   432 LYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQIPLKLS-RQGLLQPEKPIVLKV 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	152/487 (31%)
Cyp3a41a	NP_059092.2	p450	39..494	CDD:278495	153/491 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.720