Protein Alignment Cyp6a8 and Cyp4d14

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 536
• Identity: 126/536 - (23%)
• Similarity: 228/536 - (42%)
• Gaps: 76/536 - (14%)

  Fly    11 AVALLAILTYYIHRKLTYFKR---------RGIPFV--APHLIRGNMEELQKTKNIHEIFQDHYN 64
            |:.|...|.:...||..:.|.         :..|.|  ||.||    .|..|:|:  .||...:.
  Fly     7 AILLATALAWDYMRKRRHNKMYAEAGIRGPKSYPLVGNAPLLI----NESPKSKS--SIFDMQFR 65

  Fly    65 KFRE----SKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLD 125
            ...|    .|...:|...|.:..:.:|:..::.|..|:       |...|:...:.:...|....
  Fly    66 LIAEFGKNIKTQMLGESGFMTADSKMIEAIMSSQQTIQ-------KNNLYSLLVNWLGDGLLISQ 123

  Fly   126 GAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTV---MHEKVPKNSVLEIRDLVARFTVDVI 187
            |.:|...|..::..|   ..|::...|.....:..|:   ::::....:|:.:..:.....:|:|
  Fly   124 GKKWFRRRKIITPAF---HFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMDII 185

  Fly   188 GTCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRS-----------YPKLARKLGMVR 241
            ...|.|::.|:  ..:.:|.|.   ..|......|...||..           ||||..||.  .
  Fly   186 AETAMGVKINA--QLQPQFTYV---QSVTTASAMLAERFMNPLQRLDFTMKLFYPKLLDKLN--D 243

  Fly   242 TAPHIQEFYSRIVTETVAVREKEHIKRNDFMDMLIELKNQK----------EMTLENGDVVRGLT 296
            ...::.:|.:.::||...:.:|......|....|:....||          :.|::...    |:
  Fly   244 AVKNMHDFTNSVITERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKSTIDGAP----LS 304

  Fly   297 MEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVI-EQHDQNFTYECTKDLK 360
            .:::..:...|...|.:|::|::.|..|.||::|::|.:|..||.:|| :......|.:...:||
  Fly   305 NDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELK 369

  Fly   361 YLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHH---DPSIYPEPFE 422
            ||..|:.|:|||:..||.:.|..::..|:.|.   :|.|..:|||   .|:|   ||..:|:|.:
  Fly   370 YLECVIKESLRLFPSVPIIGRYISQDTVLDGK---LIPADSNVII---LIYHAQRDPDYFPDPEK 428

  Fly   423 FRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYD 487
            |.|:|||.|........|:.||..|||||||.:|..::.:..::.::|:|:.....:...|::..
  Fly   429 FIPDRFSMERKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQPVLNV 493

  Fly   488 PKSFVLGVKDGIYLKV 503
            ......|:..|:..:|
  Fly   494 ILRSTTGINCGLKPRV 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	107/457 (23%)
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	106/458 (23%)