Protein Alignment Cyp6a8 and Cyp6d4

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_651082.1
• Gene: Cyp6d4 / 42682
• FlyBaseID: FBgn0039006
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 528
• Identity: 162/528 - (30%)
• Similarity: 289/528 - (54%)
• Gaps: 51/528 - (9%)

  Fly     5 YILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLIR-GNMEEL-QKTKNIHEIFQDHYNKFR 67
            :.|..:||.||.:..:|:.|...|::|||.||.....|. |.::.: ::.|::.....|.|.|
  Fly     2 FSLILLAVTLLTLAWFYLKRHYEYWERRGFPFEKHSGIPFGCLDSVWRQEKSMGLAIYDVYVK-- 64

  Fly    68 ESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLL 132
             ||...:|.:....||..:.|.:||:::|.:||::|.::|::.:|:.||:||::|:|.|..||.:
  Fly    65 -SKERVLGIYLLFRPAVLIRDADLARRVLAQDFASFHDRGVYVDEERDPLSANIFSLRGQSWRSM 128

  Fly   133 RNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSV--LEIRDLVARFTVDVIGTCAFGIQ 195
            |:.||..|||||:|.|:.|...:.::.:..:.:::|:...  ::|:.::..:.:|:|.:..||:.
  Fly   129 RHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVMQNYAIDIIASTIFGLD 193

  Fly   196 CNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLG-MVRTAPHIQEFYSR------- 252
            .||..:...:|     |.||         ...|:..:.....| |:...|.|.:|..|
  Fly   194 VNSFENPDNKF-----RKLV---------SLARANNRFNAMFGMMIFLVPSIAQFLFRIGFKNPV 244

  Fly   253 ------IVTETVAVREKEHIKRNDFMDMLIELKN--------QKEMTLE---NGDVVRGLTMEEV 300
                  ||.|||..|||..|.|.|.:.:||:|:|        :|..:::   :|. ::.:::|.:
  Fly   245 GLAMLQIVKETVEYREKHGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQKTPDGH-IKTISLEAI 308

  Fly   301 LAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQV 365
            .||||:|:|||.||:.||..|.:||||:.|::..:::.||:|.:.::|...||:....:::|:..
  Fly   309 TAQAFIFYIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGKITYDSLNKMEFLDLC 373

  Fly   366 LDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSP 430
            :.||:|.|..:|.|:|...:.|.|| ..|.||..|..|:|....||||...:|:|..:.|||||
  Fly   374 VQETIRKYPGLPILNRECTQDYTVP-DTNHVIPKGTPVVISLYGIHHDAEYFPDPETYDPERFS- 436

  Fly   431 EESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGV 495
            |||......|::|||:|||.||..|.|::.:::.:..:::||.....|:  :.:.::.....|..
  Fly   437 EESRNYNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSR--SEIEFENSGIALIP 499

  Fly   496 KDGIYLKV 503
            |.|:.:::
  Fly   500 KHGVRVRL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	149/492 (30%)
Cyp6d4	NP_651082.1	p450	58..500	CDD:278495	144/463 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461187
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	237	1.000	Inparanoid score	I3345
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900