Protein Alignment Cyp6a8 and Cyp12c1

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_649052.1
• Gene: Cyp12c1 / 40037
• FlyBaseID: FBgn0036806
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 509
• Identity: 121/509 - (23%)
• Similarity: 197/509 - (38%)
• Gaps: 110/509 - (21%)

  Fly    41 LIRGNMEELQKTKNIHEIFQDH----YNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFS 101
            |.||    .||....|::..|.    |.|.........|.|...| ..|..::|..:::
  Fly    52 LFRG----FQKGGEYHQLGMDDVMRLYKKQFGDICLIPGLFGMPS-TVFTFNVETFEKV------ 105

  Fly   102 NFSNKG-----------IFY-NEKDDPISAHLFNL--DGAQWRLLRNKLSSTFTSGKMKLMY-PT 151
             :..:|           |.| |::.|....:...|  :||:|...|:.::......:...:| ..
  Fly   106 -YRTEGQWPVRGGAEPVIHYRNKRKDEFFKNCMGLFGNGAEWGKNRSAVNPVLMQHRNVAIYLKP 169

  Fly   152 VVSVANEFMTVMHEKVPKNSVLEIRD------------LVARFTVDVIGTCAFGIQCNSLRDEKA 204
            :..|..:|:         |.:.||||            .:...|.:.:.|.|...:...||:...
  Fly   170 MQRVNRQFV---------NRIREIRDKESQEVPGDFMNTINHLTFESVATVALDRELGLLREANP 225

  Fly   205 EFLYFGKRSLVDKRHGTLLNGF--MRSYPKLARKLGMVRTAPHIQEFYSRIVTE---TVAVREKE 264
            .    .:.|.:.|....|::.|  :...|.|.|.:    ..|..::| ||.:.|   |.::...:
  Fly   226 P----PEASKLFKNIEVLMDSFFDLGVRPSLYRYI----PTPTYKKF-SRAMDEIFDTCSMYVNQ 281

  Fly   265 HIKR----------NDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLA--QAFVFFIAGFETSSS 317
            .|:|          ||...:|.:|                |.::..||  .|....:.|.:|:|:
  Fly   282 AIERIDRKSSQGDSNDHKSVLEQL----------------LQIDRKLAVVMAMDMLMGGVDTTST 330

  Fly   318 TMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRM 382
            .:...|..|||||:.|.::|.||...:......||.|..|.|.||..|:.|:||||.:.....|.
  Fly   331 AISGILLNLAKNPEKQQRLREEVLSKLTSLHSEFTVEDMKSLPYLRAVIKESLRLYPVTFGNARS 395

  Fly   383 AAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSV-------- 439
            |....|:.|   :.|..|..:::.:|.:..|..:||...||.|||:...:...:..|
  Fly   396 AGADVVLDG---YRIPKGTKLLMTNSFLLKDDRLYPRAKEFIPERWLRRKDDDKSDVLMNKDLNA 457

  Fly   440 -AWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNP----LVYDP 488
             .:||||.|||.|:|.|...::..:.:|.|:|||.......|..|    .:|.|
  Fly   458 FIYLPFGFGPRMCVGKRIVDLEMELTVANLVRNFHIEYNYSTEKPYKCRFLYKP 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	112/476 (24%)
Cyp12c1	NP_649052.1	CYP24A1-like	76..516	CDD:410677	113/481 (23%)