Protein Alignment Cyp6a8 and Cyp312a1

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_649030.1
• Gene: Cyp312a1 / 40005
• FlyBaseID: FBgn0036778
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 526
• Identity: 121/526 - (23%)
• Similarity: 211/526 - (40%)
• Gaps: 121/526 - (23%)

  Fly    14 LLAILTYYIHRKLTYFKRR--------------GIPF----------VAPHLIRGNMEELQKTKN 54
            ||..|:.|:   |..|:|:              .:||          |.||.:|      :.|:.
  Fly     9 LLLALSLYL---LYVFERQSRIDRLTHKWPAPPALPFIGHLHILAKLVGPHPLR------RATEM 64

  Fly    55 IHEIFQDHYNKFRESKAPFVGFFFFQSPAAFVID--------LELAKQILIK--DFSNFSN---K 106
            |:|...||..|            .:.....:::|        |..|:|:|.|  |:..|.|   :
  Fly    65 INEHLHDHRAK------------LWMGTKLYLVDCNPKDIQALCSAQQLLQKTNDYRVFENWLCE 117

  Fly   107 GIFYN--EKDDPISAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK 169
            |:|.:  ||               |...|..:...|....:|.........:...:|.:.:....
  Fly   118 GLFTSGFEK---------------WSHRRKIVMPAFNYTMIKQFVAVFEKQSRILLTNVAKFAES 167

  Fly   170 NSVLEIRDLVARFTVDVIGTCAFGIQCNSLRDEKAEFLYFGKRSLV--DKRHGTLLNGFMR---- 228
            ...::...|::.||:|.|...|.|:...|....|:|:|...|..||  |||   |.|.|.|
  Fly   168 GDQIDFLQLISCFTLDTICETALGVSVGSQSSAKSEYLDAVKSILVIIDKR---LKNIFYRNSFI 229

  Fly   229 ----SYPKLARKLGMVRTAPHIQEFYSRIVTETV--------------AVREKEHIKRN-DFMDM 274
                |:.|  |:..:::|   :..|...|:.:.:              :..|.:.:||. .|:|.
  Fly   230 FKRTSHYK--REQELIKT---LHGFTEGIIQKRIDEINQDAENRNYQSSDAELDGVKRTLCFLDT 289

  Fly   275 LIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAE 339
            |:         |..|...:.||::::..:.......||:.:::|:.|.:|.:..:|:.|.:.|.|
  Fly   290 LL---------LSKGPDGKPLTVKDIREEVDTIIFGGFDLTATTLNFFMYNMTLHPEHQQRCREE 345

  Fly   340 VEEVI-EQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSV 403
            |..|. :...:..:.|..:.|::|...:.||||:|...|...|.|.....:   .:|.|..|..|
  Fly   346 VWSVCGKDKSEPISIEQVRQLEFLEACIKETLRMYPSGPLTARKATANCTI---NDFFIPKGSDV 407

  Fly   404 IIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALL 468
            ||....:......:|:|..|:|:|::........:..::||..|.|:|:|.|:..:..::.||.|
  Fly   408 IISPIYMGRCKDFFPDPMVFKPDRWAIGAEPKIEATTFIPFMAGARSCMGQRYAMVMLKMVLAHL 472

  Fly   469 IRNFKF 474
            :|||.|
  Fly   473 LRNFLF 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	102/446 (23%)
Cyp312a1	NP_649030.1	CYP4	75..504	CDD:410721	103/451 (23%)