Protein Alignment Cyp6a8 and Cyp6d2

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_611698.1
• Gene: Cyp6d2 / 37594
• FlyBaseID: FBgn0034756
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 527
• Identity: 161/527 - (30%)
• Similarity: 279/527 - (52%)
• Gaps: 82/527 - (15%)

  Fly     6 ILFQVAVALLAILTYYIHRKLTYFKRRG-------IPFVAPHLIRGNMEELQKTKN-----IHEI 58
            ||..:.:|  .:|..|:.|..|:::|.|       |||       |.|:.:.|.:.     :.:|
  Fly     4 ILLTILIA--GLLYRYVKRHYTHWQRLGVDEEPAKIPF-------GVMDTVMKQERSLGMALADI 59

  Fly    59 FQDHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFN 123
            :..|..|       .||.:.....:..:.|.:||:||:..||::|.::|::.:|..||:||:|||
  Fly    60 YARHEGK-------IVGIYMLNKRSILIRDAQLARQIMTSDFASFHDRGVYVDEDKDPLSANLFN 117

  Fly   124 LDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVIG 188
            |.||.||.||.||:.:|:|||:|.|:.|:..|.::.:..:...:.::..:||:|::..:.||:||
  Fly   118 LRGASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHLEGALDQSDEVEIKDVMTTYAVDIIG 182

  Fly   189 TCAFGIQCNSLRDEKAEFLYFGK-----RSLVDKRHGTLLNGFMRSYP---KLARKLGMVRTAPH 245
            :..||::.:|.|:.|.||.....     .||:.|.|    |..|...|   ||..:||
  Fly   183 SVIFGLEIDSFRNPKNEFREISSSTSRDESLLLKIH----NMSMFICPPIAKLMNRLG------- 236

  Fly   246 IQEFYSRIVT-------ETVAVREKEHIKRNDFMDMLIELKNQKEMTLENGDV---------VRG 294
               :.|||:|       .|:..||:.::.|.|.:.:||.|:|..::..::..|         ::.
  Fly   237 ---YESRILTSLRDMMKRTIEFREEHNVVRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKS 298

  Fly   295 LTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHD----QNFTYEC 355
            :::|::.||||:|::||.|::::...|.||||:..|::..:.:.||:.|:.:|:    ..||||.
  Fly   299 MSIEKIAAQAFLFYVAGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEA 363

  Fly   356 TKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEP 420
            .:|||:|:..:.||:|.|..:|.|:|...:.|.||| .|.:|..|..::|....:..||..:|.|
  Fly   364 VQDLKFLDICIMETIRKYPGLPFLNRECTEDYPVPG-TNHIIAKGTPILISLFGMQRDPVYFPNP 427

  Fly   421 FEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLV 485
            ..:.|.||. ..:......|::|||:|||:||.||.|::.:::.:|.::.||          .||
  Fly   428 NGYDPHRFD-SNNMNYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANF----------DLV 481

  Fly   486 YDPKSFV 492
            ..|:..|
  Fly   482 QSPRKEV 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	149/487 (31%)
Cyp6d2	NP_611698.1	p450	65..506	CDD:278495	144/457 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461163
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	237	1.000	Inparanoid score	I3345
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900