Protein Alignment Cyp6a8 and Cyp12b2

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 545
• Identity: 117/545 - (21%)
• Similarity: 207/545 - (37%)
• Gaps: 146/545 - (26%)

  Fly    32 RGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQIL 96
            |.:.|..|.....|...:|..:.:.|::.|.|         .:.....:..|.|..:.:
  Fly    63 RMLSFFMPGGALRNTNLIQMNRLMREMYGDIY---------CIPGMMGKPNAVFTYNPD------ 112

  Fly    97 IKDFS-NFSNKGIFYNEKDDPISAHLFNLD---------------------GAQWRLLRNKLSST 139
              ||. .:.|:|::      ||...|.:|:                     |.:|..:|||::
  Fly   113 --DFEMTYRNEGVW------PIRIGLESLNYYRKIHRPDVFKGVGGLASDQGQEWADIRNKVN-- 167

  Fly   140 FTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVIGTCAFGIQCNSLRDEKA 204
                      |.::.|.|     :.:.:|:      .|.:::..:|.:.|     |.|
  Fly   168 ----------PVLMKVQN-----VRQNLPQ------LDQISKEFIDKLET-----QRN------- 199

  Fly   205 EFLYFGKRSLVDKRHGTLLNGFMR----------SYPKLARKLGMV---------RTAPHIQEFY 250
                       .:.| ||...|..          |:..|..::|::         |.|.|:::|:
  Fly   200 -----------PETH-TLTTDFHNQLKMWAFESISFVALNTRMGLLSDNPDPNADRLAKHMRDFF 252

  Fly   251 SRIVTETVAVREKEHIKRNDFMDMLIELKNQKEMTL-----------ENGDVVRGLTMEEVL--- 301
            :......|........|...|...|....|..::|.           :|.|......:|::|
  Fly   253 NYSFQFDVQPSIWTFYKTAGFKKFLKTYDNITDITSNYIETAMRGFGKNDDGKTKCVLEQLLEHN 317

  Fly   302 -----AQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKY 361
                 .......:||.:|:||.....||.||:||..|:|:|.|:..::.....:.|.:.||::.|
  Fly   318 KKVAVTMVMDMLMAGIDTTSSACLTILYHLARNPSKQEKLRRELLRILPTTKDSLTDQNTKNMPY 382

  Fly   362 LNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPE 426
            |...:.|.||:.:|.|...|:..|..|:.|   :.:..|..|::....:.:|...:.:..||.||
  Fly   383 LRACIKEGLRITSITPGNFRITPKDLVLSG---YQVPRGTGVLMGVLELSNDDKYFAQSSEFIPE 444

  Fly   427 RF-----SPEESA-----GRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTP 481
            |:     :|:..|     .|....:||||.|||.|||.|..:::....|..|:|::|.|...:|
  Fly   445 RWLKSDLAPDIQACPAARTRNPFVYLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPET- 508

  Fly   482 NPLVYDPKSFVLGVKDGIYLKVETV 506
             |:.|: .:.:|.....|..|:|.|
  Fly   509 -PIEYE-STIILSPCGDIRFKLEPV 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	112/533 (21%)
Cyp12b2	NP_611370.2	p450	59..511	CDD:299894	111/522 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910