Protein Alignment Cyp6a8 and Cyp4aa1

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_611067.2
• Gene: Cyp4aa1 / 36752
• FlyBaseID: FBgn0034053
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 492
• Identity: 113/492 - (22%)
• Similarity: 208/492 - (42%)
• Gaps: 51/492 - (10%)

  Fly     1 MALTYILFQVAVAL-----LAILTYYIHRKLTYFKRRG---IPFVAPHLIRGNMEELQKTKNIHE 57
            :.|..||..:.::|     .|.|..|:...|...:..|   :||:...::..:.:.:::...  :
  Fly    13 LELCSILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTDKDLMRRCAG--K 75

  Fly    58 IFQDHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLF 122
            .| |.|............||....|.    ||:     :|......:||..||....:.:...|.
  Fly    76 AF-DLYGSLVRIWVLLFPFFAVLEPE----DLQ-----VILSSKKHTNKVFFYRLMHNFLGDGLI 130

  Fly   123 NLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSV---LEIRDLVARFTV 184
            ...|::|...|..:...|....::....|.|..:..    ::|.:...:|   :.|...|....:
  Fly   131 TSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQS----LYENLDAEAVGTEINIAKYVNNCVL 191

  Fly   185 DVIGTCAFGIQCNSLRDEKA--EFLYFGKRSLVDKRHGT----LLNGFMRSYPKLARKLGMVRTA 243
            |::.....|:.......:.|  |...|.:..::.....|    ||:|... :.|:|.  ..:...
  Fly   192 DILNEAVLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYH-WTKMAN--DELNQK 253

  Fly   244 PHIQEFYSRIVTETVAVREKE--HIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFV 306
            ..:.:|..:::.....::...  :.:|...:|.:||:....          |..|.|:::.:|..
  Fly   254 KRLNDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEISESN----------RDFTEEDIVNEACT 308

  Fly   307 FFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLR 371
            |.:||.::..:.:.|.|:.|.:||:.||:...|:..:.|..::..|.....:::|:...:.|.||
  Fly   309 FMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYMEMCIKEALR 373

  Fly   372 LYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGR 436
            ||..||.:.|...:...:..|   .:.||.:|.|...|.|....|||:|.:|:|||||||.|..|
  Fly   374 LYPSVPLIARKLGEEVRLAKH---TLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPENSENR 435

  Fly   437 PSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFK 473
            ...|:|||..|||.|||.||..|:.:..::.|:|:::
  Fly   436 HPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQ 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	99/415 (24%)
Cyp4aa1	NP_611067.2	CYP4	81..498	CDD:410721	99/421 (24%)