Protein Alignment Cyp6a8 and Cyp6a21

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0033981
• Length: 504
• Species: Drosophila melanogaster
• Alignment Length: 497
• Identity: 277/497 - (55%)
• Similarity: 367/497 - (73%)
• Gaps: 5/497 - (1%)

  Fly    13 ALLAILTYYIHR---KLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFRESKAPFV 74
            ||||::.|.:.:   .:.:::..|||...||::.|:|:.::..::.:||:..:|||||.| .||.
  Fly    10 ALLALVGYLLMKWRSTMRHWQDLGIPCEEPHILMGSMKGVRTARSFNEIWTSYYNKFRGS-GPFA 73

  Fly    75 GFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRNKLSST 139
            ||::|:.||.||::..||||||||:|:.|:::|.|:|.:|||:|..||.|||.:||.:|||||||
  Fly    74 GFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDDPLSGQLFLLDGQKWRTMRNKLSST 138

  Fly   140 FTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVIGTCAFGIQCNSLRDEKA 204
            |||||||.|:||||.|||||..|..:.|.|:.|:|:|:|:||||.||||||||||:|:||:|..|
  Fly   139 FTSGKMKYMFPTVVKVANEFTDVFGQNVAKSPVVEVRELLARFTTDVIGTCAFGIECSSLKDPDA 203

  Fly   205 EFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIVTETVAVREKEHIKRN 269
            ||...|:|||.::|.|.:..||:.|:|.|||:|.|..||..|:.|:.|||.||||.||:.:|:||
  Fly   204 EFREMGRRSLTEQRLGPVGIGFVNSFPNLARRLHMKMTAEPIERFFMRIVRETVAFREQNNIRRN 268

  Fly   270 DFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQD 334
            ||||.||:|||:..|..::|:.| .||:||:.|||||||.|||||||:||||||||||:|.|||:
  Fly   269 DFMDQLIDLKNKPLMVSQSGESV-NLTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQN 332

  Fly   335 KVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEA 399
            :||.|.:||||:.:....||..|||.||:||:.|||||||::|.|:|...:.|.|||||.:||:.
  Fly   333 RVRKECQEVIEKCNGELNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHPKYVIKK 397

  Fly   400 GQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIG 464
            |..|:||..|:|.|..:|..|..|.|:.||||....|.||.|||||||||||||:||||||||||
  Fly   398 GMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIG 462

  Fly   465 LALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLKVETV 506
            |||||::||||.|.||..|:.|:.:.|::....|||||.|.|
  Fly   463 LALLIKDFKFSVCEKTTIPMTYNKEMFLIASNSGIYLKAERV 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	266/463 (57%)
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	265/465 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471791
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	12	11.800