Protein Alignment Cyp6a8 and Cyp6a20

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_611002.3
• Gene: Cyp6a20 / 36664
• FlyBaseID: FBgn0033980
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 509
• Identity: 240/509 - (47%)
• Similarity: 345/509 - (67%)
• Gaps: 11/509 - (2%)

  Fly     1 MALTYILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNK 65
            ||:..:|.   :.::..:.:|:|:...|:||||||...|.:..||..||.||.:..:||:..|||
  Fly     1 MAVMIVLL---IGVITFVAWYVHQHFNYWKRRGIPHDEPKIPYGNTSELMKTVHFADIFKRTYNK 62

  Fly    66 FR-ESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQW 129
            .| ::..|||||:.:......|.|::.||.:||::|..|.::|:|:||:|||:||:|.|:||.:|
  Fly    63 LRNKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERDDPLSANLVNIDGQKW 127

  Fly   130 RLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNS-VLEIRDLVARFTVDVIGTCAFG 193
            :.||.||:.||||||||.|:||:::|.:|.:.|..|....:| .:||.::|||||.||||:||||
  Fly   128 KTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETASADSDSMEITNVVARFTADVIGSCAFG 192

  Fly   194 IQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIVTETV 258
            :.|:||.|.||:|:..|..::.::|||..::..:...|:||.||.|..|...:::||..|:.:||
  Fly   193 LDCHSLSDPKAKFVQMGTTAITERRHGKSMDLLLFGAPELAAKLRMKATVQEVEDFYMNIIRDTV 257

  Fly   259 AVREKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFAL 323
            ..|.|.::||:||:|||||:|    :..:|||...|||..|:.||||:||:|||||||:||||||
  Fly   258 DYRVKNNVKRHDFVDMLIEMK----LKFDNGDKENGLTFNEIAAQAFIFFLAGFETSSTTMGFAL 318

  Fly   324 YELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYV 388
            ||||.:.|||||:|.|:..|::||:....|:..:::.||.:|:|||:|...:|.:|.|:|.:.|
  Fly   319 YELACHQDIQDKLRTEINTVLKQHNGKLDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHY- 382

  Fly   389 VPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIG 453
            ...:|.:.||.|..||:|:.||||||..||||.:|.||||..::...||:..:||||||||||||
  Fly   383 QHTNPKYNIEKGTGVIVPTLAIHHDPEFYPEPEKFIPERFDEDQVQQRPACTFLPFGDGPRNCIG 447

  Fly   454 LRFGQMQARIGLALLIRNFKFS-TCSKTPNPLVYDPKSFVLGVKDGIYLKVETV 506
            ||||:||..:|:||||.||||. ..:||..||.|....|:|..|.||:|||..|
  Fly   448 LRFGRMQVIVGMALLIHNFKFEFHPTKTVVPLEYRTDDFLLSSKGGIHLKVTRV 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	225/466 (48%)
Cyp6a20	NP_611002.3	p450	32..496	CDD:278495	225/468 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D24075at7147
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	11	10.870