Protein Alignment Cyp6a8 and Cyp6a19

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 503
• Identity: 234/503 - (46%)
• Similarity: 337/503 - (66%)
• Gaps: 7/503 - (1%)

  Fly     6 ILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFR-ES 69
            ||..:.|.:|.::.:::.:..||:||||||...|::..||..||.:|..:..|.:..|.||| ::
  Fly     3 ILLGLVVGVLTLVAWWVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRTYLKFRKQT 67

  Fly    70 KAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRN 134
            ..||.||:.:......:.|::..|.:||:||..|.::|:::||||||::.:|..::|.:|:.||.
  Fly    68 DGPFAGFYLYAMKYIVITDVDFVKTVLIRDFDKFHDRGVYHNEKDDPLTNNLATIEGQKWKNLRQ 132

  Fly   135 KLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNS-VLEIRDLVARFTVDVIGTCAFGIQCNS 198
            ||:.||||.|||.|:.||::|.:|.:.|:.||:..:| .||:.|:|:|||.||||.||||::|||
  Fly   133 KLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVSRFTSDVIGICAFGLKCNS 197

  Fly   199 LRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIVTETVAVREK 263
            |||.||||:..|..:|.::|||.|::..:...||||.|||.....|.:|:||.:||.:|:..|.|
  Fly   198 LRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPSVQKFYMKIVQDTIDYRMK 262

  Fly   264 EHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAK 328
            ..:.||||||.||::|.|    .:.||...||...||.|||||||:||||..|:||||.|||||.
  Fly   263 RKVTRNDFMDTLIDMKQQ----YDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMGFTLYELAC 323

  Fly   329 NPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHP 393
            |.|:|||:|||::.|:|:::....|:..:||.|:.:|::|:||.:.:|.:|.|:|.|.| ...:|
  Fly   324 NQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLRKHPVVAHLARIATKPY-QHSNP 387

  Fly   394 NFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQ 458
            .:.||||..|::.:..|||||..||||.:|.||||..|:...||:.|:||||.|||||||||||:
  Fly   388 KYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIPERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGR 452

  Fly   459 MQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLKVETV 506
            ||..|||||||.||:|....|||.|:.|...:.:||.:.||:|.:..|
  Fly   453 MQVIIGLALLIHNFRFELHPKTPVPMKYTINNLLLGSEGGIHLNITKV 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	221/465 (48%)
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	221/467 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471823
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D24075at7147
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	12	11.800