Protein Alignment Cyp6a8 and Cyp6a23

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_611000.2
• Gene: Cyp6a23 / 36661
• FlyBaseID: FBgn0033978
• Length: 502
• Species: Drosophila melanogaster
• Alignment Length: 501
• Identity: 249/501 - (49%)
• Similarity: 354/501 - (70%)
• Gaps: 7/501 - (1%)

  Fly     6 ILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFRESK 70
            :|..:...|:::|.:...|:..|::|||||...||.|.|||::..|.::|..||:|:|.|::.|.
  Fly     3 LLLTLIALLVSLLLFMARRRHGYWQRRGIPHDVPHPIYGNMKDWPKKRHIAMIFRDYYTKYKRSV 67

  Fly    71 APFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRNK 135
            .||.||:||.:.:|.:.||||.|::|||||::|.|:||||||.|||:||.||:::|.:||.||:|
  Fly    68 YPFAGFYFFFTRSAVITDLELVKRVLIKDFNHFENRGIFYNEIDDPLSATLFSIEGQKWRHLRHK 132

  Fly   136 LSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVP--KNSVLEIRDLVARFTVDVIGTCAFGIQCNS 198
            |:.||||||||.|:|.:|.|..|...:...|..  :..||||.|||||:|.||||.||||:.|||
  Fly   133 LTPTFTSGKMKNMFPIIVKVGEEMEKIFSAKTTTGEGQVLEIVDLVARYTADVIGNCAFGLNCNS 197

  Fly   199 LRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIVTETVAVREK 263
            |::..|||:..|||:::::|:|.||:..:..:|||:|:|.:......:::||:.||..|:..|.:
  Fly   198 LQNPNAEFVTIGKRAIIERRYGGLLDFLIFGFPKLSRRLRLKLNVQDVEDFYTSIVRNTIDYRLR 262

  Fly   264 EHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAK 328
            .:.||:||||.|||:..:::.    |:...||:..|:|||||:||:|||||||:||||||||||.
  Fly   263 TNEKRHDFMDSLIEMYEKEQA----GNTEDGLSFNEILAQAFIFFVAGFETSSTTMGFALYELAL 323

  Fly   329 NPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHP 393
            :.||||::|||:..|:.:|:..||||..|::|||.||:.||||.|.::.:|.||....: .|..|
  Fly   324 DQDIQDQLRAEINNVLSKHNNEFTYEGIKEMKYLEQVVMETLRKYPVLAHLTRMTQTDF-SPEDP 387

  Fly   394 NFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQ 458
            .:.|..|.:|:||:..||:||.|||||.:|:||||:.|..|.|||..|||||:|||||||||||.
  Fly   388 KYFIAKGTTVVIPALGIHYDPEIYPEPEKFKPERFTDEAIAARPSCTWLPFGEGPRNCIGLRFGL 452

  Fly   459 MQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLKVE 504
            |||.:|||.|||.:|||..::|..|:.:..||.:|..::||:||||
  Fly   453 MQACVGLAYLIRGYKFSVSTETQIPMKFVVKSILLSAENGIHLKVE 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	220/431 (51%)
Cyp6a23	NP_611000.2	CYP6-like	68..494	CDD:410679	220/430 (51%)