Protein Alignment Cyp6a8 and Cyp301a1

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_610796.1
• Gene: Cyp301a1 / 36378
• FlyBaseID: FBgn0033753
• Length: 553
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 100/505 - (19%)
• Similarity: 195/505 - (38%)
• Gaps: 87/505 - (17%)

  Fly     6 ILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLI-RGNMEELQKTKNIHEIFQDHYNKFRES 69
            |:.|..::.:|.::..:|.:.....|.|.....|.|: ..:.:|::|...     .:....||.|
  Fly    93 IIGQYTISDVAKISSLLHDRYGRIVRFGGLIGRPDLLFIYDADEIEKCYR-----SEGPTPFRPS 152

  Fly    70 KAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRN 134
            ....|.:                |.::.||         |:.:....:..|     |..||..|:
  Fly   153 MPSLVKY----------------KSVVRKD---------FFGDLGGVVGVH-----GEPWREFRS 187

  Fly   135 KLSSTF--TSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVL--EIRDLVARFTVDVIGTCAFGIQ 195
            ::....  .|...:.:.|..| :..:|:......:.:|..|  :..:.:.:::::.||..|...:
  Fly   188 RVQKPVLQLSTIRRYLQPLEV-ITEDFLVRCENLLDENQELPEDFDNEIHKWSLECIGRVALDTR 251

  Fly   196 CNSLR------DEKAEFLYFGKRSLVDKRHGTLLNGFMRSYP-----KLARKLGMV--RTAPHIQ 247
            ...|.      .|..:.:...|.:|.:.....|...:.|.:|     :..:.:...  ....:||
  Fly   252 LGCLESNLKPDSEPQQIIDAAKYALRNVATLELKAPYWRYFPTPLWTRYVKNMNFFVGVCMKYIQ 316

  Fly   248 EFYSRIVTETVAVR--EKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIA 310
            ....|:.|:..::|  |...:::     :::..|::|..|:...|::                :.
  Fly   317 SATERLKTQDPSLRAGEPSLVEK-----VILSQKDEKIATIMALDLI----------------LV 360

  Fly   311 GFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTI 375
            |.:|.|..:...||:||..|..|.||..|::.::...:...|......:.:|...:.|..|:|:.
  Fly   361 GIDTISMAVCSMLYQLATRPVDQQKVHEELKRLLPDPNTPLTIPLLDQMHHLKGFIKEVFRMYST 425

  Fly   376 VPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPS-- 438
            |....|...:..|:.|   :.:..|...:.|:....:......:...|||||:...:..|.|.
  Fly   426 VIGNGRTLMEDSVICG---YQVPKGVQAVFPTIVTGNMEEYVTDAATFRPERWLKPQHGGTPGKL 487

  Fly   439 --VAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVY 486
              .|.||:|.|.|.|:|.||..::.:|.||.|:||:|.....|   ||.|
  Fly   488 HPFASLPYGYGARMCLGRRFADLEMQILLAKLLRNYKLEYNHK---PLDY 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	87/440 (20%)
Cyp301a1	NP_610796.1	CYP24A1-like	110..547	CDD:410677	97/488 (20%)