Protein Alignment Cyp6a8 and Cyp49a1

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_610588.2
• Gene: Cyp49a1 / 36105
• FlyBaseID: FBgn0033524
• Length: 589
• Species: Drosophila melanogaster
• Alignment Length: 422
• Identity: 102/422 - (24%)
• Similarity: 174/422 - (41%)
• Gaps: 76/422 - (18%)

  Fly   119 AHLFNLDGAQWRLLRNKLSSTFTSGKMKLMY-PTVVSVANEFMTVMH------EKVPKNSVLEIR 176
            |.|..:.|.:|...|.::.......:....| |.:..:|:|||..:.      :::|.|.:.|:
  Fly   200 AGLIGVHGPKWEAFRQEVQHILLQPQTAKKYIPPLNDIASEFMGRIELMRDEKDELPANFLHEL- 263

  Fly   177 DLVARFTVDVIGTCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVR 241
               .::.::.:|..:...:...|..|.:|    ..:.:::     .:|.|..:.|:|..::.:.|
  Fly   264 ---YKWALESVGRVSLDTRLGCLSPEGSE----EAQQIIE-----AINTFFWAVPELELRMPLWR 316

  Fly   242 TAPHIQEFYSRIVTETVAVREKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEV------ 300
            ..|            |.|.|  ..:|..|....:......|.|...:.|..|||:..|.
  Fly   317 IYP------------TKAYR--SFVKALDQFTAICMKNIGKTMDKADADEARGLSKSEADISIVE 367

  Fly   301 ----------LAQ--AFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTY 353
                      ||.  |...|:.|.:|:|......:|:||||||.|.|:..|:::|....:.:...
  Fly   368 RIVRKTGNRKLAAILALDLFLVGVDTTSVAASSTIYQLAKNPDKQKKLFDELQKVFPHREADINQ 432

  Fly   354 ECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYP 418
            ...:.:.||...:.||||:..:|....|......|:.|   :.:..|..||.|...:.:||:.:|
  Fly   433 NVLEQMPYLRACVKETLRMRPVVIANGRSLQSDAVING---YHVPKGTHVIFPHLVVSNDPAYFP 494

  Fly   419 EPFEFRPERFSPE--ESAGRPSV-------AWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKF 474
            ||..|.|||:..:  ::||.|..       ..||||.|.|.|:|.||.:::....||.:.|.:|.
  Fly   495 EPKRFLPERWLKQSTDAAGCPHANQKIHPFVSLPFGFGRRMCVGRRFAEIELHTLLAKIFRKYKV 559

  Fly   475 STCSKTPNPLVY---------DPKSFVLGVKD 497
            |..|   ...||         .|.:|.|.::|
  Fly   560 SYNS---GEFVYRVNSTYIPQSPLNFKLTLRD 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	102/422 (24%)
Cyp49a1	NP_610588.2	CYP24A1-like	138..581	CDD:410677	99/413 (24%)