Protein Alignment Cyp6a8 and Cyp4e2

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 569
• Identity: 131/569 - (23%)
• Similarity: 240/569 - (42%)
• Gaps: 119/569 - (20%)

  Fly     1 MALTYILFQVAVALLAILTYYIHRKLTYFK-RRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYN 64
            :||..:|    ||.|.:.|:...|.|..|. .||:|      :.||..  |..||..||....::
  Fly     9 LALPLLL----VAYLELSTFRRRRVLNKFNGPRGLP------LMGNAH--QMGKNPSEILDTVFS 61

  Fly    65 KFRE-SKAPFVGFFFFQS----PAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNL 124
            .:.: .|..||.:....|    .::..::..|:.|.||       .|...|......:...|...
  Fly    62 WWHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLI-------TKSDIYQLTHPWLGLGLLTS 119

  Fly   125 DGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK-----------NSVLEIRDL 178
            .|::|...|..::..|.           .::..:|..||:|...|           :::.:.::.
  Fly   120 TGSKWHKHRKMITPAFH-----------FNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQ 173

  Fly   179 VARFTVDVIGTCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTA 243
            ....|:|||...|.|:..|::.:..:        |:|........|..||::..|.|...:.|.|
  Fly   174 AHYLTLDVICDTAMGVSINAMENRSS--------SIVQAFKDMCYNINMRAFHPLKRNELLYRLA 230

  Fly   244 PH----------IQEFYSRIVTETVAVREKEHI----------KRNDFMDMLIELKNQKEMTLEN 288
            |.          :|:|.:.|:.:.:...:...:          |:..|:|.|:      ..|::.
  Fly   231 PDYPAYSRTLKTLQDFTNEIIAKRIEAHKSGAVSTNAGDEFTRKKMAFLDTLL------SSTIDG 289

  Fly   289 GDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHD--QNF 351
                |.|..:|:..:...|...|.:|::|.:.||:|.|:::.|.|.|:..|..||:...:  ::.
  Fly   290 ----RPLNSKELYEEVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDA 350

  Fly   352 TYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSI 416
            |::....:|||:..:.|..|:|..||.:.|...|.||:.|.   ::..|.::.:....:.::..:
  Fly   351 TFQEISQMKYLDLFIKEAQRVYPSVPFIGRFTEKDYVIDGD---LVPKGTTLNLGLVMLGYNEKV 412

  Fly   417 YPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFK-------- 473
            :.:|.:||||||..|:..   ...::||..|||||||.:|..::.:..::.:||||:
  Fly   413 FKDPHKFRPERFELEKPG---PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDEL 474

  Fly   474 ------FSTC---------SKTPNPLVYDP-KSFVLGVK--DGIYLKVE 504
                  .||.         .:.|....||| .|.||.:|  :|:|::::
  Fly   475 VSKDGYISTTIGLPDAERKKRDPYRHKYDPILSAVLTLKSENGLYIRLK 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	118/527 (22%)
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	109/483 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810