Protein Alignment Cyp6a8 and Cyp6a2

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_523628.1
• Gene: Cyp6a2 / 35587
• FlyBaseID: FBgn0000473
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 275/505 - (54%)
• Similarity: 370/505 - (73%)
• Gaps: 3/505 - (0%)

  Fly     5 YILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFRES 69
            ::|..:.:|:.::|.|..||...|:.|||:|..|||.:.|||...:|.:.:|:.|.|:|||:|:|
  Fly     2 FVLIYLLIAISSLLAYLYHRNFNYWNRRGVPHDAPHPLYGNMVGFRKNRVMHDFFYDYYNKYRKS 66

  Fly    70 KAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRN 134
            ..|||||:|...||||::|.:|||.|||||||||:::|.|:|.:|||::.|||||||.:|:.:|.
  Fly    67 GFPFVGFYFLHKPAAFIVDTQLAKNILIKDFSNFADRGQFHNGRDDPLTQHLFNLDGKKWKDMRQ 131

  Fly   135 KLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVP---KNSVLEIRDLVARFTVDVIGTCAFGIQC 196
            :|:.||||||||.|:|||:.|:.||:.|:.|:||   ..:||||::|:||||.||||||||||:|
  Fly   132 RLTPTFTSGKMKFMFPTVIKVSEEFVKVITEQVPAAQNGAVLEIKELMARFTTDVIGTCAFGIEC 196

  Fly   197 NSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIVTETVAVR 261
            |:||...::|...|::...|.|||.||..|:.|:||||.:|.|......:.:|:.|:|.:|:|:|
  Fly   197 NTLRTPVSDFRTMGQKVFTDMRHGKLLTMFVFSFPKLASRLRMRMMPEDVHQFFMRLVNDTIALR 261

  Fly   262 EKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYEL 326
            |:|:.||||||::|||||.:..:||:||:|:.|:.:.|:.||.|||::||||||||||.:.||||
  Fly   262 ERENFKRNDFMNLLIELKQKGRVTLDNGEVIEGMDIGELAAQVFVFYVAGFETSSSTMSYCLYEL 326

  Fly   327 AKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPG 391
            |:|.||||::|.|::.|:|:.:...|||..|.:.|||||:.|||||||:||:|:|.|...|||||
  Fly   327 AQNQDIQDRLRNEIQTVLEEQEGQLTYESIKAMTYLNQVISETLRLYTLVPHLERKALNDYVVPG 391

  Fly   392 HPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRF 456
            |...|||.|..||||:.|.|.|..:||.|..|.|||||||:.|.|.||.|||||||||||||:||
  Fly   392 HEKLVIEKGTQVIIPACAYHRDEDLYPNPETFDPERFSPEKVAARESVEWLPFGDGPRNCIGMRF 456

  Fly   457 GQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLKVETV 506
            ||||||||||.:|..|:.|.|..|..||.|.|.|.|||...||||:||.:
  Fly   457 GQMQARIGLAQIISRFRVSVCDTTEIPLKYSPMSIVLGTVGGIYLRVERI 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	261/466 (56%)
Cyp6a2	NP_523628.1	p450	36..502	CDD:278495	260/465 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471793
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	1	1.000	-	-		H130979
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	12	11.800