Protein Alignment Cyp6a8 and Cyp4e3

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 555
• Identity: 124/555 - (22%)
• Similarity: 241/555 - (43%)
• Gaps: 100/555 - (18%)

  Fly    10 VAVALLAILTYYIHRKLTYFKRRGI-----------PFVAPHLIRGNMEELQKT-KNIHEIFQDH 62
            :|:.:|.::|      |.||:|:..           |...|  |.||...:.|. ..|...|.|.
  Fly     6 LALLVLPLIT------LVYFERKASQRRQLLKEFNGPTPVP--ILGNANRIGKNPAEILSTFFDW 62

  Fly    63 YNKFRESKAPFVGFFFFQSPAAFVIDLELAKQI-LIKDFSNFSNKGIFYNEKDDPISAHLFNLDG 126
            :..:.:.     .|.|:...::.:: :...||: .|.:......|...|:.....:...|....|
  Fly    63 WYDYGKD-----NFLFWIGYSSHIV-MTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFG 121

  Fly   127 AQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVIGTCA 191
            ::|...|..::.:|....::..:..:...:.:|||.:.:....:::::.::.....|:|||...|
  Fly   122 SKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTA 186

  Fly   192 FGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPH----------I 246
            .|:..|::....:        |:|........|..||::....|...:....|.          :
  Fly   187 MGVPINAMEQRDS--------SIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTLKTL 243

  Fly   247 QEFYSRIVTETVAV-----REKEH-----IKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVL 301
            |:|...|:.:.|..     .:::|     .|:..|:|.|:      ..|::.    |.||.:|:.
  Fly   244 QDFTYDIIEKRVYALQNGGSKEDHDPSLPRKKMAFLDTLL------SSTIDG----RPLTRQEIY 298

  Fly   302 AQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQN--FTYECTKDLKYLNQ 364
            .:...|...|.:|::|.:.|::|.|:::||:|.|:..|..||: .||.|  .:::....:|||:.
  Fly   299 EEVSTFMFEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVM-GHDMNRSVSFQEIAKMKYLDL 362

  Fly   365 VLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFS 429
            .:.|..|:|..||.:.|...|.|.:.|.   ::..|.::.:....:.::..|:.:|..||||||.
  Fly   363 FIKEAQRVYPSVPFIGRYCDKDYDINGS---IVPKGTTLNLALILLGYNDRIFKDPHHFRPERFE 424

  Fly   430 PEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFK--------FSTCSK------- 479
            .|:.|   ...:|||..|||||||.:|..::.:..::.::|:|:        .||..:
  Fly   425 EEKPA---PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGL 486

  Fly   480 TPNPLV--------YDP-KSFVLGVK--DGIYLKV 503
            .|:..:        ||| .|.||.:|  :|::|::
  Fly   487 APDEKLKREAGRHKYDPILSAVLTLKSDNGLHLRL 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	116/513 (23%)
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	105/465 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810