Protein Alignment Cyp6a8 and Cyp28d2

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_608911.1
• Gene: Cyp28d2 / 33748
• FlyBaseID: FBgn0031688
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 530
• Identity: 146/530 - (27%)
• Similarity: 243/530 - (45%)
• Gaps: 76/530 - (14%)

  Fly     8 FQVAVALLAILTY-YIHRKLTYFKRRGI------PFVAPHLIRGNMEEL-QKTKNIHEIFQDHYN 64
            |.|.|..|.:|.| ::.....|:::|||      |||      |:...: .:.:||.....|.|.
  Fly     7 FLVLVLTLLVLVYVFLTWNFNYWRKRGIKTAPTWPFV------GSFPSIFTRKRNIAYDIDDIYE 65

  Fly    65 KFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNK--GIFYNEKDDPI-SAHLFNLDG 126
            |::::. ..||.|..:.|...|:..|...:|...||.:|.|.  ..|.|:|.|.| ..:.|.|.|
  Fly    66 KYKDTD-NMVGVFTTRVPQLLVMCPEYIHKIYATDFRSFHNNEWRNFVNKKTDMILGNNPFVLTG 129

  Fly   127 AQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVM--HEKVPKNSVLEIRDLVARFTVDVIGT 189
            .:|:..|:::....:..::|.:||...||..:|:..:  .:::..:..|:..||...:|.:|:..
  Fly   130 DEWKERRSEIMPALSPNRVKAVYPVSQSVCKKFVEYIRRQQQMATSEGLDAMDLSLCYTTEVVSD 194

  Fly   190 CAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNG-----FMRSYPKLARKLGMVRTAPHIQE- 248
            |..|:...|..|.....|...||         :.|.     |......|.:|:....:.|...:
  Fly   195 CGLGVSAQSFTDTPTPLLKMIKR---------VFNTSFEFIFYSVVTNLWQKVRKFYSVPFFNKE 250

  Fly   249 ---FYSRIVTETVAVR-EKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFI 309
               |:..|:...:.:| ||...:|:||::.:::|:.:|           ||..:.:|.....|.:
  Fly   251 TEVFFLDIIRRCITLRLEKPEQQRDDFLNYMLQLQEKK-----------GLHTDNILINTMTFIL 304

  Fly   310 AGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYT 374
            .||||::..:...:..|.:||:.|||||.|:...      :.|::...:|.:|:..:.|||||::
  Fly   305 DGFETTALVLAHIMLMLGRNPEEQDKVRKEIGSA------DLTFDQMSELPHLDACIYETLRLFS 363

  Fly   375 IVPNLDRMAAKRYVVPGHP-NFV--------IEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSP 430
                 .::||::.|.  .| .|.        ::.|..|.||..|:||||..|.:|..|:||||..
  Fly   364 -----PQVAARKLVT--EPFEFANKNGRTVHLKPGDVVTIPVKALHHDPQYYEDPLTFKPERFLE 421

  Fly   431 EESAGRPSV----AWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSF 491
            ....|..|.    .:|.||||||:|.|:||...|.:..|..::|||:.....||.:....|...|
  Fly   422 SNGGGMKSYRDRGVYLAFGDGPRHCPGMRFALTQLKAALVEILRNFEIKVNPKTRSDNQIDDTFF 486

  Fly   492 VLGVKDGIYL 501
            :..:|.||||
  Fly   487 MATLKGGIYL 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	124/457 (27%)
Cyp28d2	NP_608911.1	CYP6-like	74..495	CDD:410679	124/453 (27%)