Protein Alignment Cyp6a8 and Cyp6t1

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_608457.1
• Gene: Cyp6t1 / 33127
• FlyBaseID: FBgn0031182
• Length: 529
• Species: Drosophila melanogaster
• Alignment Length: 529
• Identity: 171/529 - (32%)
• Similarity: 268/529 - (50%)
• Gaps: 66/529 - (12%)

  Fly     6 ILFQVAVALLAILTYYIHRKLTYFKRRGIPFV--AP------HLIRGNMEELQKTKNIHEIFQDH 62
            :|....|.|..||.::      :::|.|:|||  ||      :|:||..           .|.|.
  Fly    29 LLVVTIVWLWQILHFW------HWRRLGVPFVPAAPFVGNVWNLLRGAC-----------CFGDQ 76

  Fly    63 YNKFRESK----APFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPI-----S 118
            :.:..|||    ..|||.....:.|..:.|..|.|:|:::||:.||::    .|..||.     |
  Fly    77 FRELYESKEAAGRAFVGIDVLHNHALLLRDPALIKRIMVEDFAQFSSR----FETTDPTCDTMGS 137

  Fly   119 AHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVP-KNSV-LEIRDLVAR 181
            .:||......||......:..|.:||::.||..:.::..:....|.:|:. ::|: ||::.|.|.
  Fly   138 QNLFFSKYETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQKLSGRDSMELEVKQLCAL 202

  Fly   182 FTVDVIGTCAFGIQCNSLRDEKAEFLYFGKRSLV---DKRHGTLLNGF-MRSYPKLARKLGMVRT 242
            ||.|:|.:.||||:.:||::.:|||    :|..:   |.|...||:.| |..:|:|:.::|....
  Fly   203 FTTDIIASLAFGIEAHSLQNPEAEF----RRMCIEVNDPRPKRLLHLFTMFFFPRLSHRVGTHLY 263

  Fly   243 APHIQEFYSRIVTETVAVREKEHIKRNDFMDMLIELKNQK--EMTLENGDVVRGLTMEEVLAQAF 305
            :...:.|..:.:...::.|.:....|:|.:|:.::||..:  |..:...|.        ..|||.
  Fly   264 SEEYERFMRKSMDYVLSQRAESGENRHDLIDIFLQLKRTEPAESIIHRPDF--------FAAQAA 320

  Fly   306 VFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIE-QHDQNFTYECTKDLKYLNQVLDET 369
            ...:|||:|||||:.|||||||||..|||::|.|:...:: ..|:..:.:....|.||.||:||.
  Fly   321 FLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQSSQDRQLSCDTVTGLVYLRQVVDEV 385

  Fly   370 LRLYTIVPNLDRMAAKRY---VVP---GHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERF 428
            ||||.....|||....|.   :.|   |.| |.:.||..|.|....||.|...:|.|..|.||||
  Fly   386 LRLYPPTAFLDRCCNSRTGYDLSPWNGGSP-FKLRAGTPVYISVLGIHRDAQYWPNPEVFDPERF 449

  Fly   429 SPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVL 493
            |.|:......:.:||||.|||.|||...||::.::||..::.:|:...|.:|...:.:|||:|||
  Fly   450 SAEQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILNHFRVEVCERTLPEMRFDPKAFVL 514

  Fly   494 GVKDGIYLK 502
            ...:|.||:
  Fly   515 TAHNGTYLR 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	150/453 (33%)
Cyp6t1	NP_608457.1	CYP6-like	88..521	CDD:410679	149/449 (33%)