Protein Alignment Cyp6a8 and LOC3290579

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_061502574.1
• Gene: LOC3290579 / 3290579
• VectorBaseID: AGAMI1_012923
• Length: 507
• Species: Anopheles gambiae
• Alignment Length: 588
• Identity: 147/588 - (25%)
• Similarity: 237/588 - (40%)
• Gaps: 175/588 - (29%)

  Fly     1 MALTYILFQVAVALLAILTYYIHRKLTYFKRRG-------------IPFVA-PHLIRGNMEELQK 51
            :.|.|::..:|:|.|..|.:         |||.             :||:. .:|:.|.    |.
Mosquito     6 LVLMYVVLSLALATLLCLRW---------KRRKLYAAAATMDGPPCVPFLGHAYLLFGK----QT 57

  Fly    52 TKNIHEIFQDHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDP 116
            .::|.|:| |.|       ||     .:.||....:..:|.  :.|||     |...|....:.|
Mosquito    58 GEHIIEVF-DKY-------AP-----RYNSPIGIWMGPKLI--VAIKD-----NPEYFQKVMNSP 102

  Fly   117 ISAHL------FNLDGAQ----------WRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHE 165
               ||      :|...|:          |:..|..|:.:|:    .:|..:.|.:.|:...|:.|
Mosquito   103 ---HLLSKMDQYNFFRAENGLLTAPEHVWKTERKLLNRSFS----PMMLSSFVDIFNKKDLVLVE 160

  Fly   166 KVPK-------NSVLEIRDLVARFTVDVIGTCAF----GIQCNSLRDEKAE----FLYFGKRSLV 215
            .:.|       ||.|    .:::.|:|.:...||    |.|.:...||..:    ||     |||
Mosquito   161 NLRKFVGAGVFNSQL----YISKCTIDALFENAFGRDIGTQAHDGHDEYLQCLDTFL-----SLV 216

  Fly   216 DKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRI-------VTETVAVREKEHIKRNDFMD 273
            .||                        ..|::.:...|       .||:..|    :|.||..:|
Mosquito   217 FKR------------------------VLHVERYLECIYRLTKDYATESSCV----NIIRNMSLD 253

  Fly   274 MLIELK-NQKEMTLENGDVVRG--------------------LTMEEVLAQAFVFFIAGFETSSS 317
            ::.|:| |..:...:..:...|                    ||.:.:........:||.:|:::
Mosquito   254 LMKEVKENAHQAQQQPVEEAYGGKPALNFAHSLSSLAKHNPSLTEDHIKDHIDTMIMAGHDTTAT 318

  Fly   318 TMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRM 382
            |:...|..||.:|::|:.|..||..|.....:..|.|...:|.|...|..||:||:.:.|.:.|.
Mosquito   319 TIANLLLMLAMHPEVQEMVYQEVMSVCPDKSKPVTMEDANNLAYTEMVCKETMRLFPVAPVIGRK 383

  Fly   383 AA------KRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIY-PEPFEFRPERFSPEESAGRPSVA 440
            .|      .::.:|        ||..|.:....||.||.|: |||.:|.|:.|.||..|.|...|
Mosquito   384 CAADVKLDDKHTIP--------AGCCVALGIYQIHRDPMIWGPEPGKFNPDHFLPERVAERHPYA 440

  Fly   441 WLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPK----SFVLGVKDGIYL 501
            :|||..|||||||:|:..:..:|.:|.|:||::|.|      |||.:..    :.||.:.:|.::
Mosquito   441 YLPFSGGPRNCIGIRYAWLSMKIMIAHLVRNYRFKT------PLVMEDLVLKFAIVLRITNGCFV 499

  Fly   502 KVE 504
            .:|
Mosquito   500 SIE 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	127/499 (25%)
LOC3290579	XP_061502574.1	None