Protein Alignment Cyp6a8 and Cyp4s3

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_573003.2
• Gene: Cyp4s3 / 32444
• FlyBaseID: FBgn0030615
• Length: 495
• Species: Drosophila melanogaster
• Alignment Length: 527
• Identity: 129/527 - (24%)
• Similarity: 205/527 - (38%)
• Gaps: 81/527 - (15%)

  Fly    10 VAVALLAILTYYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFRESKAPFV 74
            ||..|.|....|:.:.|.:.:.:......|....|   ||.......||. :...:.||...|..
  Fly     7 VAFVLWAAFLRYLPKILNFLRLQRFAKTLPGPTIG---ELIANVKKGEIL-NWLKELREKHGPVF 67

  Fly    75 GFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRNKLSST 139
            ..:|.:.......|.|..||:|  ..:....|...|...:..:...|....|..|...|..|:..
  Fly    68 RIWFGKDLMVMFTDPEDIKQLL--GNNQLLTKSRNYELLEPWLGKGLLTNGGESWHRRRKLLTPG 130

  Fly   140 FTSGKMKLMYPTVVSVANEFMTVMHEKV----------PKNSVLEIRDLVARFTVDVIGTCAFGI 194
            |.           ..:.:||...|.|..          ......:|...:..|.:|.|...|.||
  Fly   131 FH-----------FRILSEFKEPMEENCRILVRRLRTKANGESFDIYPYITLFALDAICETAMGI 184

  Fly   195 QCNSLRDEKAEFLYFGKRSLVDKRH------GTLLNGFMR-SYPKLARKLGM------------V 240
            :.::.....:|::. ..:|:....|      ...||.|.: :.|...|:..:            :
  Fly   185 KKHAQLQSDSEYVQ-AVQSICRVMHKQSFSFWQRLNVFFKHTKPGKEREAALKVLHDETNRVIRL 248

  Fly   241 RTAPHIQEFYSRIVTETVAVREKEHI---KRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLA 302
            |....|||     ..|.....|::.:   :|..|:|||:..:.:....|.:.|:     .|||
  Fly   249 RREQLIQE-----RNEWKPEAEQDDVGAKRRLAFLDMLLLTQMEGGAELSDTDI-----REEV-- 301

  Fly   303 QAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLD 367
            ..|:|  .|.:|:||.:.|||..|:||||:|.:...|..| :|..::       :.:.||..|:.
  Fly   302 DTFMF--EGHDTTSSAIAFALSLLSKNPDVQQRAFEEASE-LEGREK-------ESMPYLEAVIK 356

  Fly   368 ETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEE 432
            ||||:|..||...|...:...|   ....:..|.|:......:|.||..:|:|..|.|:||...|
  Fly   357 ETLRIYPSVPFFSRKVLEDLEV---GKLTVPKGASISCLIYMLHRDPKNFPDPERFDPDRFLVNE 418

  Fly   433 SAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKF-STCSKTPNPLVYDPKSFVLGVK 496
            ....| .|:..|..|||||||.:|..::.:..||:|:|:::| ......|.||.    ..|....
  Fly   419 KQMHP-FAFAAFSAGPRNCIGQKFAMLELKTSLAMLLRSYRFLPDKDHQPKPLA----ELVTKSG 478

  Fly   497 DGIYLKV 503
            :||.|::
  Fly   479 NGIRLRI 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	113/462 (24%)
Cyp4s3	NP_573003.2	CYP4	64..483	CDD:410721	114/462 (25%)