Protein Alignment Cyp6a8 and Cyp4ae1

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_525044.1
• Gene: Cyp4ae1 / 31193
• FlyBaseID: FBgn0015036
• Length: 496
• Species: Drosophila melanogaster
• Alignment Length: 529
• Identity: 119/529 - (22%)
• Similarity: 227/529 - (42%)
• Gaps: 72/529 - (13%)

  Fly     1 MALTYILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLIRGNMEELQ--KTKNIHEIFQDHY 63
            |.:..::..:...|:|.|.....::|.:..:..:|.|:...:.|...:::  :..|:|:.|.::.
  Fly     1 MLVVLLVALLVTRLVASLFRLALKELRHPLQGVVPSVSRVPLLGAAWQMRSFQPDNLHDKFAEYV 65

  Fly    64 NKF-RESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGA 127
            .:| |......:|.....:.....||..|..|..:|       ||..|......:...|....|.
  Fly    66 KRFGRSFMGTVLGHVVMVTAEPRHIDALLQGQHQLK-------KGTMYFALRGWLGDGLLLSRGK 123

  Fly   128 QWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK----NSVLEIRDLVARFTVDVIG 188
            :|..:|..::.||....::    ..|.|.:...:::.|::..    |.|:.|..||....:|:|.
  Fly   124 EWHTMRKIITPTFHFSILE----QFVEVFDRQSSILVERLRTLSYGNEVVNIYPLVGLAALDIIT 184

  Fly   189 TCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRS---YPKLAR----------KLGMV 240
            ..|.|:..:: :...:|.::     .|......|...|||.   :|.|.|          :.|::
  Fly   185 ETAMGVNVDA-QGADSEVVH-----AVKDLTNILATRFMRPHLLFPHLFRLCWPSGFRKQQAGVI 243

  Fly   241 RTAPHIQEFYSRIVTE--TVAVREKEH---IKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEV 300
                .:.||.:.|:.:  .:..||...   .|.:..:|.|:      ..|::.    :.||.:::
  Fly   244 ----CLHEFTNGIIEQRRRLLAREANQDKPTKPHALLDTLL------RATVDG----QPLTDKQI 294

  Fly   301 LAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQN-FTYECTKD---LKY 361
            ..:...|...|.:|::|.:.|.||.|:::..:|.|:   .||:...:.|: |......|   |.|
  Fly   295 RDEVNTFIFEGHDTTTSAVSFCLYLLSRHEAVQQKL---FEELRMHYGQDLFRGVILSDFATLPY 356

  Fly   362 LNQVLDETLRLYTIVPNLDRMAAKRYVV-PGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRP 425
            |:.|:.|:||||..:|.:.|...|..|: .|:    |..|.:|::....:..|.:|:.:|..|:|
  Fly   357 LSCVVKESLRLYPPIPAVARCLEKDLVIDEGY----IPVGTNVVVLLWQLLRDEAIFTDPLVFQP 417

  Fly   426 ERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKS 490
            ||...||:......:::||..|||||||.:|..::.:..:..:||:::.........|.:    .
  Fly   418 ERHLGEEAPRLSPYSYIPFSAGPRNCIGQKFALLEMKTMVTKVIRHYQLLPMGADVEPSI----K 478

  Fly   491 FVLGVKDGI 499
            .||..|.|:
  Fly   479 IVLRSKSGV 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	106/457 (23%)
Cyp4ae1	NP_525044.1	CYP4	76..489	CDD:410721	106/454 (23%)