Protein Alignment Cyp6a8 and Cyp4d2

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001284806.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 120/560 - (21%)
• Similarity: 226/560 - (40%)
• Gaps: 135/560 - (24%)

  Fly     6 ILFQVAVALLAILTYYIHRKLTYFKRRG---------IPFVAPHLIRGNMEELQKTKNIHEIFQD 61
            :|..||.|.|.:..:       .::|||         :||:...|:...::.        |...|
  Fly     7 VLLLVAFATLLLWDF-------LWRRRGNGILPGPRPLPFLGNLLMYRGLDP--------EQIMD 56

  Fly    62 HYNKFRESKAPFVGFFFFQSPAAFVID-----------LELAKQILIKDFSNFSNKGIFYNEKDD 115
            ...|.:.........:.....|.|..|           ..:.|..|.|..:.:...|:..:
  Fly    57 FVKKNQRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMS---- 117

  Fly   116 PISAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPT--------VVSVANEFMTVMHEKVPKN-- 170
                     .|.:|.            |:.|::.||        .|.:.::...||.|::...
  Fly   118 ---------TGRKWH------------GRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRAD 161

  Fly   171 --SVLEIRDLVARFTVDVIGTCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKL 233
              :.:.|..::....:|:|...|.|.:.|:.::....::     ..|:.....|:..|:.::.::
  Fly   162 GMTPINIFPVICLTALDIIAETAMGTKINAQKNPNLPYV-----QAVNDVTNILIKRFIHAWQRV 221

  Fly   234 ARKLGMVRTAPHIQEFYSRIVTETVAVREKEHIK-RNDFMDMLIE------LKNQKEMTLENG-- 289
                          ::..|:...|.|.|:.:.|| .:||.:.:|.      :.|.||.|.|..
  Fly   222 --------------DWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEVN 272

  Fly   290 -----------DVVRGLTM-------EEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKV 336
                       ||:...|:       |::..:...|...|.:|::|.:.|.|||::::|::|.::
  Fly   273 FLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRL 337

  Fly   337 RAEVEEVI-EQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPG-HPNFVIEA 399
            :.|:.:|: |......|.....:||::..|:.|:|||:..||.:.|..|:...:.| |    |.|
  Fly   338 QQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKH----IPA 398

  Fly   400 GQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIG 464
            |.:..:....:..||..:..|.|||||||..:.....| .|::||..|||||||.:|..::.:..
  Fly   399 GTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQIHP-YAYIPFSAGPRNCIGQKFAMLEMKST 462

  Fly   465 LALLIRNFKFSTCSKTPNPLVYDPK---SFVLGVKDGIYL 501
            ::.|:|:|:..       ||..:|:   :.||...:|::|
  Fly   463 VSKLLRHFELL-------PLGPEPRHSMNIVLRSANGVHL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	110/518 (21%)
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	111/526 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810