Protein Alignment Cyp6a8 and Cyp4f4

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_775146.1
• Gene: Cyp4f4 / 286904
• RGDID: 708363
• Length: 522
• Species: Rattus norvegicus
• Alignment Length: 462
• Identity: 121/462 - (26%)
• Similarity: 210/462 - (45%)
• Gaps: 63/462 - (13%)

  Fly    75 GFFFFQSPAAFVIDL---ELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRNKL 136
            ||..:..|...:|.|   ::.:.:|....|....:.|||:.....:...|...||.:|...|..|
  Rat    87 GFMTWLGPILPIITLCHPDVIRSVLSASASVALKEVIFYSFLKPWLGDGLLLSDGDKWSCHRRML 151

  Fly   137 SSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK-----NSVLEIRDLVARFTVDVIGTCAFGIQC 196
            :..|....:|    ..|.:.|:...:||.|...     ::.|::...::..|:|.:..|.|....
  Rat   152 TPAFHFNILK----PYVKIFNDSTNIMHAKWQDLASGGSARLDMFKNISLMTLDSLQKCVFSFDS 212

  Fly   197 NSLRDEKAEFL--YFGKRSLVDKRHGTLL-----------NGFMRSYPKLARKLGMVRTAPHIQE 248
            | .:::.:|::  .....:||.||:..||           ||  |.:.| |.||        :..
  Rat   213 N-CQEKPSEYISAILELSALVAKRYQQLLLHTDSLYQLTHNG--RRFHK-ACKL--------VHN 265

  Fly   249 FYSRIVT----------ETVAVREKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQ 303
            |...::.          |...::.|...|..||:|:|:..|:      |:|   :.|:.|::.|:
  Rat   266 FTDAVIQGRRRALPSQHEDDILKAKARSKTLDFIDVLLLTKD------EDG---KELSDEDIRAE 321

  Fly   304 AFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVI-EQHDQNFTYECTKDLKYLNQVLD 367
            |..|...|.:|::|.:.:.||.||::|:.|::.|.||.|:: ::......::....|.:|...:.
  Rat   322 ADTFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVRELLRDRESTEIEWDDLAQLPFLTMCIK 386

  Fly   368 ETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEE 432
            |:|||:..|..:.|...:..|:|  ...||..|...||...|.||:|:::|:|..:.|.||.||.
  Rat   387 ESLRLHPPVTVISRRCTQDIVLP--DGRVIPKGVICIINIFATHHNPTVWPDPEVYDPFRFDPEN 449

  Fly   433 SAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKD 497
            ...|..:|::||..|||||||..|...:.::.|||.:..|:.....|.|.    .....:|..:.
  Rat   450 IKDRSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRFRVLPDDKEPR----RKPELILRAEG 510

  Fly   498 GIYLKVE 504
            |::|:||
  Rat   511 GLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	118/456 (26%)
Cyp4f4	NP_775146.1	CYP4F	74..515	CDD:410772	118/458 (26%)