Protein Alignment Cyp6a8 and Cyp4f6

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_006241111.1
• Gene: Cyp4f6 / 266689
• RGDID: 708365
• Length: 538
• Species: Rattus norvegicus
• Alignment Length: 397
• Identity: 107/397 - (26%)
• Similarity: 189/397 - (47%)
• Gaps: 38/397 - (9%)

  Fly   126 GAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEK----VPKNSV-LEIRDLVARFTVD 185
            |.:|...|..|:..|....:|    :.|.:.|:.:..||.|    ..|.|. |::.:.::..|:|
  Rat   142 GEKWNHHRRLLTPAFHFDILK----SYVKIFNKSVNTMHAKWQRLTAKGSARLDMFEHISLMTLD 202

  Fly   186 VIGTCAFGIQCNSLRDEKAEFL--YFGKRSLVDKRHGT--LLNGFMRSYPKLARKLGMVRTAPH- 245
            .:..|.|....| .::..:|::  .....||:.||...  |...|:.......|:........|
  Rat   203 SLQKCIFSFDSN-CQESNSEYIAAILELSSLIVKRQRQPFLYLDFLYYLTADGRRFRKACDVVHN 266

  Fly   246 -----IQEFYSRIVTETV--AVREKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQ 303
                 |:|..|.:.|:.|  .::.:...|..||:|:|:..|:      |:|   :||:..::.|:
  Rat   267 FTDAVIRERRSTLNTQGVDEFLKARAKTKTLDFIDVLLLAKD------EHG---KGLSDVDIRAE 322

  Fly   304 AFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVI-EQHDQNFTYECTKDLKYLNQVLD 367
            |..|...|.:|::|.:.:.||.||::|:.|::.|.||.|:: ::..:...::....|.:|...:.
  Rat   323 ADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCIK 387

  Fly   368 ETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEE 432
            |:|||:..|..:.|..::..|:|  ...||..|...:|....:||:||::|:|..:.|.||.||.
  Rat   388 ESLRLHPPVLLISRCCSQDIVLP--DGRVIPKGNICVISIFGVHHNPSVWPDPEVYNPFRFDPEN 450

  Fly   433 SAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKD 497
            ...|..:|::||..|||||||..|...:.::.|||.:..|......|.|.    .....:|..:.
  Rat   451 PQKRSPLAFIPFSAGPRNCIGQTFAMSEIKVALALTLLRFCVLPDDKEPR----RKPELILRAEG 511

  Fly   498 GIYLKVE 504
            |::|:||
  Rat   512 GLWLRVE 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	104/391 (27%)
Cyp4f6	XP_006241111.1	CYP4F	75..516	CDD:410772	104/393 (26%)