Protein Alignment Cyp6a8 and Cyp26b1

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_780684.1
• Gene: Cyp26b1 / 232174
• MGIID: 2176159
• Length: 512
• Species: Mus musculus
• Alignment Length: 501
• Identity: 110/501 - (21%)
• Similarity: 192/501 - (38%)
• Gaps: 97/501 - (19%)

  Fly    33 GIPFVAP--H-LIRGNMEELQKTKNIHEIFQDHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQ 94
            |.|.:..  | |::|:..:..:.:....:|:.|               ....|...|...|..::
Mouse    55 GFPLIGETGHWLLQGSGFQSSRREKYGNVFKTH---------------LLGRPLIRVTGAENVRK 104

  Fly    95 ILIKDFSNFSNKGIFYNEKDDPISAHLF-------NLDGAQWRLLRNKLSSTFTSGKMKLMYPTV 152
            ||:.:....|.:.        |.||.:.       |..|...|..|...|..|:...::...|.:
Mouse   105 ILLGEHQLVSTEW--------PRSARVLLGPNTVANSIGDIHRNKRKVFSKIFSHEALESYLPKI 161

  Fly   153 VSVANEFMTVMHEKVPK--NSVLEIRDLVARFTVDVIGTCAFGIQCNSLRDEKAEFLYFGKRSLV 215
            ..|..:.:.....: |:  |...|.:.|..|..|.|:    .|.   |:.:|....|:...:..|
Mouse   162 QLVIQDTLRAWSSQ-PEAINVYQEAQRLTFRMAVRVL----LGF---SIPEEDLGHLFEVYQQFV 218

  Fly   216 DKRHGTLL----NGFMRSYPKLARKLGMVRTAPHIQEFYSRIVTETVAVREKEHIKR----NDFM 272
            :......:    :|:.|...  ||::        :|:...:      |:|||....:    :|.:
Mouse   219 ENVFSLPVDLPFSGYRRGIQ--ARQI--------LQKGLEK------AIREKLQCTQGKDYSDAL 267

  Fly   273 DMLIELKNQ--KEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDK 335
            |:|||...:  |||           ||:|:.........|.:.|::|.....:.:|.|:|.:.:|
Mouse   268 DILIESSKEHGKEM-----------TMQELKDGTLELIFAAYATTASASTSLIMQLLKHPAVLEK 321

  Fly   336 VRAEVEEVIEQHDQNFTYECT------KDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPN 394
            :|.|:......|......|.|      ..|:||:.|:.|.:||:|.|....|...:.:.:.|
Mouse   322 LREELRAQGLLHGGGCPCEGTLRLDTLSSLRYLDCVIKEVMRLFTPVSGGYRTVLQTFELDG--- 383

  Fly   395 FVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFS---PEESAGRPSVAWLPFGDGPRNCIGLRF 456
            |.|..|.||:......|....::.:...|.|:|||   .|:..||  ..:||||.|.|.|:|...
Mouse   384 FQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGR--FHYLPFGGGVRTCLGKHL 446

  Fly   457 GQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLK 502
            .::..::....|....:|...::|...:...|   ||...||:.:|
Mouse   447 AKLFLKVLAVELASTSRFELATRTFPRITLVP---VLHPVDGLSVK 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	102/457 (22%)
Cyp26b1	NP_780684.1	CYP26B1	60..490	CDD:410730	108/496 (22%)