Protein Alignment Cyp6a8 and cyp-13A7

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_496114.1
• Gene: cyp-13A7 / 188362
• WormBaseID: WBGene00000372
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 549
• Identity: 142/549 - (25%)
• Similarity: 250/549 - (45%)
• Gaps: 96/549 - (17%)

  Fly     6 ILFQVAVALLAILTYYIHRKLTYFKR-----RGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYN- 64
            ||..:|: .:.|::||:.....:.::     ||:||:..               ||: |.::.|
 Worm     5 ILIAIAI-FVGIISYYLWIWSFWIRKGVKGPRGLPFLGV---------------IHK-FTNYENP 52

  Fly    65 ---KFRE---SKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDD------PI 117
               ||.|   ...|..|..........:.|.|...::.:|.|.||..:.:...:.|.      |:
 Worm    53 GALKFSEWTKKYGPVYGITEGVEKTLVISDPEFVHEVFVKQFDNFYGRKLTAIQGDPNKNKRVPL 117

  Fly   118 SAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARF 182
            .|    ..|.:|:.||...|.||::..::.:..||.....|.:..:.:...:...|::.:....|
 Worm   118 VA----AQGHRWKRLRTLASPTFSNKSLRKIMGTVEESVTELVRSLEKASAEGKTLDMLEYYQEF 178

  Fly   183 TVDVIGTCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNG----FMRS--YP-------KLA 234
            |:|:||..|.|       .||:  |.| :..::||.......|    ||.|  :|       .:.
 Worm   179 TMDIIGKMAMG-------QEKS--LMF-RNPMLDKVKTIFKEGRNNVFMISGIFPFVGIALRNIF 233

  Fly   235 RKLGMVRTAPHIQEFYSRIVTETVAVREKEHI-------KRNDFMDMLIELKN-------QKEMT 285
            .|...::.|..||....:.:.:.:..||.:..       :..||:|:.::.::       :.|..
 Worm   234 AKFPSLQMATDIQSILEKALNKRLEQREADEKAGIEPSGEPQDFIDLFLDARSTVDFFEGEAEQD 298

  Fly   286 LENGDVV---RGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQH 347
            ....:|:   :.||.:|::.|.|||.:||::|::.::.::.|.||.:|:||.|::.||:.  |..
 Worm   299 FAKSEVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEVDR--ECP 361

  Fly   348 DQNFTYECTKDLKYLNQVLDETLRLY---TIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSA 409
            |...|::....||||..|:.|.||||   ::|.|  |...|...|.|   ..||||.::.:.:.:
 Worm   362 DPEVTFDQLSKLKYLECVVKEALRLYPLASLVHN--RKCLKTTNVLG---MEIEAGTNINVDTWS 421

  Fly   410 IHHDPSIYPEPF-EFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFK 473
            :||||.::.:.. ||:|||:...:........:||||.|||.|||:|...|:.::.|..:::|:.
 Worm   422 LHHDPKVWGDDVNEFKPERWESGDELFFAKGGYLPFGMGPRICIGMRLAMMEMKMLLTNILKNYT 486

  Fly   474 FSTCSKTPNPL------VYDPKSFVLGVK 496
            |.|..:|..||      ...|.|.:|.:|
 Worm   487 FETTPETVIPLKLVGTATIAPSSVLLKLK 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	132/511 (26%)
cyp-13A7	NP_496114.1	p450	33..499	CDD:278495	132/502 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.730