Protein Alignment Cyp6a8 and cyp-13A1

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001369869.1
• Gene: cyp-13A1 / 188361
• WormBaseID: WBGene00011677
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 519
• Identity: 142/519 - (27%)
• Similarity: 233/519 - (44%)
• Gaps: 83/519 - (15%)

  Fly    15 LAILTYYIHRKLTYFKRRGI--PFVAPHL------IRGN----MEELQKTKNIHEIFQDHYNKFR 67
            :|:.:|||. :.|:::|||:  |...|.|      :..|    ::..:.||...:|:
 Worm    14 VAVFSYYIW-QWTFWRRRGVVGPMGFPVLGVFLNSLDNNFPFPLQCREWTKKFGKIY-------- 69

  Fly    68 ESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPIS--------AHLFNL 124
                   ||.........:.|.||..::.:..:.|      ||..|.:||.        .:||..
 Worm    70 -------GFTEGTLKTLVISDPELVHEVFVTQYDN------FYGRKRNPIQGDSEKEKRTNLFAA 121

  Fly   125 DGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVIGT 189
            .|.:|:.||...|.||::..::.:|.||...|.|.:..:.::......:::......||:||||.
 Worm   122 QGFRWKRLRAISSPTFSNSSLRKLYQTVEDSALELLRHIEKQSAGGKQIDMLKFYQEFTLDVIGR 186

  Fly   190 CAFGIQCNSLRDEK-----AEFLY---FGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHI 246
            .|.| |.:|...:.     ...|:   |.|..|:.....|.|...:|.......|:|..|....|
 Worm   187 IAMG-QTDSQMFKNPIMPIVSKLFQGNFAKLFLIGGIFPTFLVEIIRQILLKNLKVGSFRKINEI 250

  Fly   247 --QEFYSRIVTETVAVREKEHIKRN--------DFMDMLIELKNQ--KEMTLENGD-------VV 292
              ...::||       :::|..::|        ||:|:.::.|.:  :.....|||       ..
 Worm   251 TLDAIHNRI-------KQREEDQKNGIEIGEPADFIDLFLDAKAEDVEHFGENNGDFSKSTTYTN 308

  Fly   293 RGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTK 357
            |.||.||::.|..||.||||:|::.::.:|.|.||.:|:||.|::.||..  |..:...|.:...
 Worm   309 RQLTTEEIVGQCTVFLIAGFDTTALSLSYATYLLATHPEIQKKLQEEVNR--ECPNPEVTIDQLS 371

  Fly   358 DLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFE 422
            .|||:..|..|.||||.:....:.....|....|  |..:|.|..:.:.:..:|.||:|:.:..|
 Worm   372 KLKYMECVFKEALRLYPLGAFANSRRCMRNTKLG--NMKVEVGTMIQVDTWTLHTDPNIWGDDAE 434

  Fly   423 -FRPERF-SPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPL 484
             |:|||: :|..........::|||.|||.|||:|...|:.:|.|..::|.|.|.|.:||..||
 Worm   435 DFKPERWQTPNSDQIYQKSGYIPFGLGPRQCIGMRLAYMEEKILLVHILRKFTFETGAKTEIPL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	133/493 (27%)
cyp-13A1	NP_001369869.1	CYP3A-like	64..510	CDD:410678	128/468 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.730