Protein Alignment Cyp6a8 and cyp-13A8

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_496115.1
• Gene: cyp-13A8 / 188358
• WormBaseID: WBGene00011674
• Length: 509
• Species: Caenorhabditis elegans
• Alignment Length: 551
• Identity: 151/551 - (27%)
• Similarity: 254/551 - (46%)
• Gaps: 105/551 - (19%)

  Fly     6 ILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLI-----RGNMEE--------LQK-TKNIH 56
            ::|:  :.|::|:|||... .|::||||:|  .|..:     .|.|.|        ||| ||...
 Worm     1 MIFE--LILISIVTYYFWH-WTFWKRRGLP--GPWGVPIFGKAGAMLEDSFPPGYTLQKWTKEYG 60

  Fly    57 EIFQDHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISA-- 119
            :|:               ||.........:.|.:|.::||:|.:.|      ||..|.:|:..
 Worm    61 KIY---------------GFTEGMQKVMVISDPDLVQEILVKQYDN------FYGRKHNPVQGDP 104

  Fly   120 ------HLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDL 178
                  |:....|.:|:.||...:..|::|.:|.:..|:.....|.|..:.|:......:.:...
 Worm   105 DKDKDIHIVGAQGFRWKRLRTITAPAFSNGSIKKVLTTMEDSTQELMKKLREESENGKAVNMHLF 169

  Fly   179 VARFTVDVIGTCAFGIQCNS-------LRDEKAEFLYFGKRSLVDKRHGT----LLNG---FMRS 229
            ...:|.|||...|.| |.:|       |:|.|..|           .|..    :.:|   |..|
 Worm   170 YQEYTFDVISRVAMG-QPDSQMFKNPLLKDVKGFF-----------EHNRWQIWMFSGGFPFAVS 222

  Fly   230 YPK-LARKLGMVRTAPHI--QEFYSRIVTETVAVRE--KEH----IKRNDFMDMLIELKNQKEMT 285
            :.| |..|:|.....|.|  |:..:..|...:|.||  |:|    .:..|::||.:..:.:.|..
 Worm   223 FLKWLFIKVGKFGAGPFIVVQKSVTDAVMSRIAQREADKKHGVEPGEAADYIDMFLNARAEVEHF 287

  Fly   286 LENGDVV--------RGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEE 342
            .|:.|..        |.||.:|:::|.|||.:|||:|::.::.:..|.||.||.||.|::.||::
 Worm   288 GESNDEFHKSSSYNNRQLTTQEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQSKLQDEVDK 352

  Fly   343 VIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPS 407
              |..:...|::....|||::.|:.|:|||:......:.....|..|.|..  ::|||..|:|.:
 Worm   353 --ECPNDEITFDQLSKLKYMDNVIKESLRLFPFASFANSRRCMRNTVIGEQ--IVEAGVDVMIDT 413

  Fly   408 SAIHHDPSIYPEPF-EFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRN 471
            ..:|||.:::.... ||:|||:   :|...|..|:|.||.|||.|:|:||..::.:..|:.:::.
 Worm   414 WTLHHDKNVWGNDVEEFKPERW---DSPLTPQQAYLSFGAGPRVCLGMRFALLEQKGLLSHILKK 475

  Fly   472 FKFSTCSKTPNPL------VYDPKSFVLGVK 496
            :.|.|.:||..|:      ...|::..|.:|
 Worm   476 YTFETNAKTQLPIKLVGRATARPENLFLSLK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	129/473 (27%)
cyp-13A8	NP_496115.1	CYP3A-like	58..500	CDD:410678	128/481 (27%)