Protein Alignment Cyp6a8 and cyp-13A4

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_496111.1
• Gene: cyp-13A4 / 188355
• WormBaseID: WBGene00011671
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 538
• Identity: 145/538 - (26%)
• Similarity: 243/538 - (45%)
• Gaps: 95/538 - (17%)

  Fly     1 MALTYILFQVAVAL-LAILTYYIHRKLTYFKR-----RGIPFVAPHLIRGNMEELQKTKNIHEIF 59
            |:|:.:   :|.|| :..|||||.....:.::     ||.||....|                .|
 Worm     1 MSLSLL---IAGALFIGFLTYYIWIWSFWIRKGVKGPRGFPFFGVIL----------------KF 46

  Fly    60 QDHYN-------KFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPI 117
            .|:.|       ::.:......|..........|.:.|...::.:|.|.|      ||..|.:||
 Worm    47 HDYENPGLLKLGEWTKKYGSIYGITEGVEKTLVVSNPEFVHEVFVKQFDN------FYGRKTNPI 105

  Fly   118 S--------AHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLE 174
            .        |||....|.:|:.||...|.||::..::.:..||.....|.|..:.|...|...::
 Worm   106 QGDPNKNKRAHLVLAQGHRWKRLRTLASPTFSNKSLRKIMSTVEETVVELMRHLDEASAKGKAVD 170

  Fly   175 IRDLVARFTVDVIGTCAFGIQCNSL---------------RDEKAEFLYFGKRSLVDKRHGTLLN 224
            :.|....||:|:||..|.| |..||               :..|..||..|...:.    |||:.
 Worm   171 LLDYYQEFTLDIIGRIAMG-QTESLMFRNPMLPKVKEIFKKGGKMPFLIAGVFPIA----GTLMR 230

  Fly   225 GFMRSYPKLARKLGMVRTAPHIQEFYSRIVTETVAVREKEHIKRN----DFMDMLIELKN----- 280
            .....:||.:...|::.|..  :....|:  |..|..:|..|:.:    ||:|:.::.:.
 Worm   231 QLFMKFPKFSPAFGIMNTME--KALNKRL--EQRAADKKAGIEPSGEPQDFIDLFLDARANVDFI 291

  Fly   281 QKEMTL-----ENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEV 340
            ::|.||     |...|.:.||.:|::.|.|||.:||::|::.::.::.|.||.:|:||.|::.||
 Worm   292 EEESTLGFAKSEVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEV 356

  Fly   341 EEVIEQHDQNFTYECTKDLKYLNQVLDETLRLY---TIVPNLDRMAAKRYVVPGHPNFVIEAGQS 402
            :.  |..|...|::....|||:..|:.|.||:|   ::|.|  |...|:..|.|   ..|:.|.:
 Worm   357 DR--ECPDPEVTFDQISKLKYMECVVKEALRMYPLASLVHN--RKCMKKTNVLG---VEIDEGTN 414

  Fly   403 VIIPSSAIHHDPSIY-PEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLA 466
            |.:.:..:|:||.:: .:..||:|||:...:........:||||.|||.|||:|...|:.::.|.
 Worm   415 VQVDTWTLHYDPKVWGDDASEFKPERWETGDELFYAKGGYLPFGMGPRICIGMRLAMMEEKLLLT 479

  Fly   467 LLIRNFKFSTCSKTPNPL 484
            .:::.:.|.|.::|..||
 Worm   480 HILKKYTFDTSTETEIPL 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	131/494 (27%)
cyp-13A4	NP_496111.1	p450	33..514	CDD:278495	135/503 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.730