Protein Alignment Cyp6a8 and cyp-13A12

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 519
• Identity: 140/519 - (26%)
• Similarity: 248/519 - (47%)
• Gaps: 61/519 - (11%)

  Fly     3 LTYILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFR 67
            :..|...:..:::.:|::|:. ..:|:|||||...:.:.|.|:..|:..::|      ..|.:.:
 Worm     1 MAIIFLAILTSIIGVLSFYLW-TWSYWKRRGIAGPSGYPILGSALEMLSSEN------PPYLQLK 58

  Fly    68 ESKAPF---VGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPIS--------AHL 121
            |....:   .|.....|....:.|.:|.:::.:|.:.|      |:..|.:||.        .:|
 Worm    59 EWTKQYGKVYGITEGLSRTLVISDPDLVQEVFVKQYDN------FFGRKLNPIQGDPNKDKRVNL 117

  Fly   122 FNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDV 186
            |:..|.:|:.||...|.||::..::.:..||...|.|.:..:.:.......:::.|....||:||
 Worm   118 FSSQGHRWKRLRTISSPTFSNNSLRKLKTTVEECAVELLRHIEQHTDGGQPIDLLDFYQEFTLDV 182

  Fly   187 IGTCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNG------------FMRSYPKLARKLGM 239
            ||..|.| |.:| :..|...|.:.:....:.|.|..|:|            .|.|.|.:.:
 Worm   183 IGRIAMG-QTDS-QMFKNPLLPYVRAVFGEPRKGLFLSGSLAPWIGPILRMVMFSLPNIVK---- 241

  Fly   240 VRTAPHIQEFYSRIVTETVAVR---EKEHI---KRNDFMDML-------IELKNQKEMTLENGDV 291
             ..|.|:....|..|.:.|.:|   ||..|   :..||:|:.       :||:|.::.|.....|
 Worm   242 -NPAVHVIRHTSNAVEQRVKLRMADEKAGIDPGEPQDFIDLFLDAKSDDVELENNEDFTKAGVKV 305

  Fly   292 VRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECT 356
            .|.||.||::.|.|||.||||:|::.::.::.:.||.:|.:|.|::.|::.  |..|...|::..
 Worm   306 TRQLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEIDR--ECADPEVTFDQL 368

  Fly   357 KDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPF 421
            ..|||:..|:.||||:|.:....:.....|....|  |:.|:.|.:::..:..:|.|.||:.|..
 Worm   369 SKLKYMECVIKETLRMYPLGALANSRCCMRATKIG--NYEIDEGTNILCDTWTLHSDKSIWGEDA 431

  Fly   422 -EFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPL 484
             ||:|||:...:........::|||.|||.|||:|...|:.::.|:.::|.:....|:||..||
 Worm   432 EEFKPERWESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHILRKYTLEVCNKTQIPL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	131/483 (27%)
cyp-13A12	NP_499705.1	p450	33..507	CDD:278495	131/486 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.730