Protein Alignment Cyp6a8 and cyp-25A1

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 530
• Identity: 144/530 - (27%)
• Similarity: 253/530 - (47%)
• Gaps: 57/530 - (10%)

  Fly     1 MALTYILFQVAVALLAILTYYIHRKLTYFKRR---GIPFVAPHLIRGNMEEL--QKTKNIHEIFQ 60
            ||| .||..:.:::.....|.|..:...||.|   |:....||...||:::.  :|.|..::...
 Worm     1 MAL-LILSSLVISIFTFFIYIILARRERFKLREKIGLSGPEPHWFLGNLKQTAERKEKLGYDDAN 64

  Fly    61 DHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGI--FYNEKDDPISAHLFN 123
            ..:|:..|......|.::.......:.:.:..|::.||:|||||::.:  .| |.:...::.|.|
 Worm    65 RWFNELHEQYGETFGIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIY-EANQLTASLLMN 128

  Fly   124 LDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVIG 188
            ...:.|:..|:.::..|::||||.|..|:.|..:.|:.::.||.......:|.|.....|:||||
 Worm   129 SYSSGWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREKASSGQKWDIYDDFQGLTLDVIG 193

  Fly   189 TCAFGIQCNSLRDEKAEFLYFGKR--SLVDKRHGTL---------LNGFMRS---YPKLA-RKLG 238
            .|||.|..|..||....|....|:  |.:|.||..:         |:.|.::   |..|| .::.
 Worm   194 KCAFAIDSNCQRDRNDVFYVNAKKYISNIDIRHSKIIAASVLLPELSTFWKALYKYTPLADAEIP 258

  Fly   239 MVRTAPHIQEFYSRIVTETVAVREKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQ 303
            :|....::.|             .:...:.:|.:|:|..|.|:::      |..:.:|.:||:..
 Worm   259 LVEGLSNVYE-------------RRRGGEGSDSVDLLKLLLNRED------DKSKPMTKQEVIEN 304

  Fly   304 AFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDE 368
            .|.|.:||:||:|:.|.:..|.|:|.|::|.|:..|:.|..|  :...||:...::|||:.|..|
 Worm   305 CFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKE--NGGLTYDSIHNMKYLDCVYKE 367

  Fly   369 TLRLY-TIVPNLDRMAAKRYVVPG--HPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSP 430
            |||.| .::..:.|:..:...:.|  :|.     |..|:.....:|.:|..:..|.||.||||..
 Worm   368 TLRFYPPVIHFIRRLCREDITIRGQFYPK-----GAIVVCLPHTVHRNPENWDSPEEFHPERFEN 427

  Fly   431 -EESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLG 494
             ||.:.  |:.|:|||.|||.|:|:||.:|:.:..:..|:..|:........: |:.|....::.
 Worm   428 WEEKSS--SLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELKQFEGEAD-LIPDCNGVIMR 489

  Fly   495 VKDGIYLKVE 504
            ..|.:.|.::
 Worm   490 PNDPVRLHLK 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	133/486 (27%)
cyp-25A1	NP_497775.3	p450	37..496	CDD:278495	132/488 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	208	1.000	Domainoid score	I1665
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I2346
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4722
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.880