Protein Alignment Cyp6a8 and CYP26A1

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_000774.2
• Gene: CYP26A1 / 1592
• HGNCID: 2603
• Length: 497
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 63/228 - (27%)
• Similarity: 101/228 - (44%)
• Gaps: 26/228 - (11%)

  Fly   270 DFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQD 334
            |.:.:||      |.:.|.|:   .|.|:.:...:......|.||::|.....:..|...|.:..
Human   269 DALQLLI------EHSWERGE---RLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQ 324

  Fly   335 KVRAEVEE----VIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNF 395
            |||.|::.    .....|.....|..:.|||:..|:.|||||...||...|:|.|.:.:.|   :
Human   325 KVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNG---Y 386

  Fly   396 VIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERF---SPEESAGRPSVAWLPFGDGPRNCIGLRFG 457
            .|..|.:||......|....|:....||.|:||   .||:::   ..:::|||.|.|:|:|..|.
Human   387 QIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDAS---RFSFIPFGGGLRSCVGKEFA 448

  Fly   458 QMQARIGLALLIRNFKFSTCSKTP----NPLVY 486
            ::..:|....|.|:..:...:..|    :|.||
Human   449 KILLKIFTVELARHCDWQLLNGPPTMKTSPTVY 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	63/228 (28%)
CYP26A1	NP_000774.2	CYP26A1	55..490	CDD:410731	63/228 (28%)