Protein Alignment Cyp6a8 and Cyp26a1

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_031837.2
• Gene: Cyp26a1 / 13082
• MGIID: 1096359
• Length: 497
• Species: Mus musculus
• Alignment Length: 475
• Identity: 102/475 - (21%)
• Similarity: 178/475 - (37%)
• Gaps: 112/475 - (23%)

  Fly    65 KFRESKAPFVGFFF----FQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAH----- 120
            ||.:.|....||.:    |..|...|:..:..::||:.:..              .:|.|
Mouse    66 KFLQMKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHR--------------LVSVHWPASV 116

  Fly   121 --------LFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHE--KVPKNSVL-- 173
                    |.||..:..:..:..:...|:...::...|.   :|.|..:.:.:  ...:..:|
Mouse   117 RTILGAGCLSNLHDSSHKQRKKVIMQAFSREALQCYVPV---IAEEVSSCLEQWLSCGERGLLVY 178

  Fly   174 -EIRDLVARFTVDVIGTCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKLARKL 237
             |::.|:.|..:.::..|..| ......||         :.||:            ::.::.|.|
Mouse   179 PEVKRLMFRIAMRILLGCEPG-PAGGGEDE---------QQLVE------------AFEEMTRNL 221

  Fly   238 ----------GMVRTAPHIQEFYSRIVTETVAVREKEHIKR----------NDFMDMLIELKNQK 282
                      |:.|........::||...   :|.|  |:|          .|.:.:||
Mouse   222 FSLPIDVPFSGLYRGVKARNLIHARIEEN---IRAK--IRRLQATEPDGGCKDALQLLI------ 275

  Fly   283 EMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEE----V 343
            |.:.|.|:   .|.|:.:...:......|.||::|.....:..|...|.:..|||.|::.    .
Mouse   276 EHSWERGE---RLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLC 337

  Fly   344 IEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSS 408
            ....|.....|..:.|||...|:.|||||...||...|:|.|.:.:.|   :.|..|.:||....
Mouse   338 KSNQDNKLDMETLEQLKYTGCVIKETLRLNPPVPGGFRVALKTFELNG---YQIPKGWNVIYSIC 399

  Fly   409 AIHHDPSIYPEPFEFRPERF---SPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIR 470
            ..|....|:....||.|:||   .||:::   ..:::|||.|.|:|:|..|.::..:|....|.|
Mouse   400 DTHDVADIFTNKEEFNPDRFIVPHPEDAS---RFSFIPFGGGLRSCVGKEFAKILLKIFTVELAR 461

  Fly   471 NFKFSTCSKTP----NPLVY 486
            :..:...:..|    :|.||
Mouse   462 HCDWQLLNGPPTMKTSPTVY 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	100/470 (21%)
Cyp26a1	NP_031837.2	CYP26A1	55..490	CDD:410731	102/475 (21%)