Protein Alignment Cyp6a8 and LOC1273103

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_312050.1
• Gene: LOC1273103 / 1273103
• VectorBaseID: AGAMI1_012639
• Length: 509
• Species: Anopheles gambiae
• Alignment Length: 510
• Identity: 220/510 - (43%)
• Similarity: 317/510 - (62%)
• Gaps: 18/510 - (3%)

  Fly     3 LTYILFQVAVALLAILTYYIHRKLTYFKRRGIPFVA-PHLIRGNMEELQKTKNIHEIFQDHYNKF 66
            |...:|.|::..|     :|..|..|:|..|.|:.. ||.:.|:.:...:|::..:|.|:.|..|
Mosquito     8 LAAFIFAVSIVYL-----FIRNKHNYWKDNGFPYAPNPHFLFGHAKGQAQTRHGADIHQELYRYF 67

  Fly    67 RESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRL 131
            ::....:.|...|..|:..|||.||||.||:|||:.|.:.|:|.|.||||::.|||.|:|..|||
Mosquito    68 KQRGERYGGISQFIVPSVLVIDPELAKTILVKDFNVFHDHGVFTNAKDDPLTGHLFALEGQPWRL 132

  Fly   132 LRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVIGTCAFGIQC 196
            :|.||:.|||||:||.|:.|:..|..|....|.:...:..| |::|::.|||.||||||||||:|
Mosquito   133 MRQKLTPTFTSGRMKQMFGTIWDVGIELEKCMEQSYNQPEV-EMKDILGRFTTDVIGTCAFGIEC 196

  Fly   197 NSLRDEKAEFLYFGKRSLVDKRHGTLLNGFM-RSYPKLARKLGMVRTAPHIQEFYSRIVTETVAV 260
            |:|:...:||..:|.::. :.....::..|: .|||.|.|.|.|..|...::.|:..||.|||..
Mosquito   197 NTLKTTDSEFRKYGNKAF-ELNTMIMMKTFLASSYPTLVRNLHMKITYNDVERFFLDIVKETVDY 260

  Fly   261 REKEHIKRNDFMDMLIELKNQKEM------TLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTM 319
            ||..::||||||::::::||:.::      :|..|:|  |:|..|:.|||||||:|||||||:|.
Mosquito   261 REANNVKRNDFMNLMLQIKNKGKLDDSDDGSLGKGEV--GMTQNELAAQAFVFFLAGFETSSTTQ 323

  Fly   320 GFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAA 384
            .|.|||||||||||:::|.|:...|.::....||:...::|||:.|:|||||.|..|.:|.|:.:
Mosquito   324 SFCLYELAKNPDIQERLREEINRAIAENGGEVTYDVVMNIKYLDNVIDETLRKYPPVESLTRVPS 388

  Fly   385 KRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPR 449
            ..|::|| ...||.....|.||:.||..||..||:|..|.|:||.|||...|....::|||:|||
Mosquito   389 VDYLIPG-TKHVIPKRTLVQIPAYAIQRDPDHYPDPERFNPDRFLPEEVKKRHPFTFIPFGEGPR 452

  Fly   450 NCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLKVE 504
            .|||||||.||.::||..|:|.|:||..::||..:.||||...:..|.|.|||||
Mosquito   453 ICIGLRFGLMQTKVGLITLLRKFRFSPSARTPERVEYDPKMITIAPKAGNYLKVE 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	197/436 (45%)
LOC1273103	XP_312050.1	CYP6-like	70..501	CDD:410679	196/435 (45%)