Protein Alignment Cyp6a8 and LOC1269358

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_003436060.2
• Gene: LOC1269358 / 1269358
• VectorBaseID: AGAMI1_003647
• Length: 508
• Species: Anopheles gambiae
• Alignment Length: 561
• Identity: 148/561 - (26%)
• Similarity: 235/561 - (41%)
• Gaps: 127/561 - (22%)

  Fly     1 MALTYILFQVAVALLAILTYYIHRKLTYFKRRGIPFVAPHL-------IRGNMEELQKTKNIHEI 58
            |||..:|..::.| ||:.|....|    :|||.:...|..:       :.|::..:...:...:|
Mosquito     1 MALQLVLLYISAA-LALATLVCVR----WKRRKLYAAAATMDGPPCLPLLGHVYLIFGKRCGEDI 60

  Fly    59 FQ--DHYNKFRESKAPFVGFFFFQSPAAFVIDLELAKQIL--IKD----FSNFSNKGIFYNEKDD 115
            .|  |.|       ||     .::||    |.:.:..|::  |||    |....|.....|:.|.
Mosquito    61 LQVLDRY-------AP-----RYKSP----IGIWMGPQLIVGIKDNPDYFQTVMNSPHMLNKMDQ 109

  Fly   116 ----PISAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK---NSVL 173
                .|...||......|:..|..|:.:|:    ..|..:.|.:.|:...:|.|.:.|   |..:
Mosquito   110 YNFFRIVNGLFAAPDHTWKNERKLLNRSFS----PTMLSSFVDIFNDKDFIMVENLRKFVGNGEV 170

  Fly   174 EIRDLVARFTVDVIGTCAFGIQCNSLRDEKA-EFL-----YFGKRSLVDKR--HGTLLNGFMRSY 230
            ::...:|:.|:|.|...|||...|:..::.| |:|     :|   |||.||  |   |..:..|.
Mosquito   171 DLHLYIAKCTIDSIFGTAFGKDLNTQGNDGADEYLHCLDTFF---SLVFKRILH---LERYSESI 229

  Fly   231 PKLARKLGMVRTAPHIQEFYSRIVTETVAVREKEHIKRNDFMDMLIELK---------------- 279
            .:|.:...:                ||..|    :|.||..:|::.|||
Mosquito   230 YRLTKDYEL----------------ETNCV----NIIRNMSLDLMKELKENYKNSKATVKEDAYE 274

  Fly   280 -----NQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAE 339
                 |..|...|..:....|..:.:........:||.:|:::||...|..||.:|::|:.|..|
Mosquito   275 RKPALNFAENLFELAENNPSLPEDHIKDHIDTMIVAGHDTTATTMSNLLLMLAMHPEVQEMVYQE 339

  Fly   340 VEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAA------KRYVVPGHPNFVIE 398
            |..|.....:..|.|...:|.|...|..||:||:.:.|.:.|...      .::.:|
Mosquito   340 VMSVCPDKSKPVTMEDVNNLVYTEMVCKETMRLFPVGPLIGRKCVADVKLDDKHTIP-------- 396

  Fly   399 AGQSVIIPSSAIHHDPSIY-PEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQAR 462
            ||..|.:....||.||:|: |||.:|.|:.|.||..|.|...|:|||..|||||||:|:..:..:
Mosquito   397 AGCCVALGIYQIHRDPTIWGPEPGKFNPDHFLPERVAERHPYAYLPFSGGPRNCIGIRYAWLSMK 461

  Fly   463 IGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIYLKV 503
            |.:|.|:||::|.|..|..:          |.:|..|.|::
Mosquito   462 ILIAHLVRNYRFKTTLKMED----------LEIKFAIILRI 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	128/478 (27%)
LOC1269358	XP_003436060.2	None