Protein Alignment Cyp6a8 and Cyp4f15

DIOPT Version :9

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_598888.1
• Gene: Cyp4f15 / 106648
• MGIID: 2146921
• Length: 534
• Species: Mus musculus
• Alignment Length: 459
• Identity: 116/459 - (25%)
• Similarity: 205/459 - (44%)
• Gaps: 50/459 - (10%)

  Fly    75 GFFFFQSPAAFVIDL---ELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRNKL 136
            ||..:..|...:|.|   ::.:.:|....|....:.:||:.....:...|...||.:|...|..|
Mouse    92 GFMTWLGPIIPIITLCHPDIIRSVLNASASVALKEVVFYSFLKPWLGDGLLLSDGDKWSSHRRML 156

  Fly   137 SSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK-----NSVLEIRDLVARFTVDVIGTCAFGIQC 196
            :..|....:|    ..|.:.|:...:||.|...     ::.|::.:.::..|:|.:..|.|....
Mouse   157 TPAFHFNILK----PYVKIFNDSTNIMHAKWQHLASGGSARLDVFENISLMTLDSLQKCVFSFDS 217

  Fly   197 NSLRDEKAEFL--YFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIVT---- 255
            | .::..:|::  .....:||.||:..||......|..........:....:..|...::.
Mouse   218 N-CQENPSEYISAILELSALVTKRYHQLLLHIDSLYQLTCSGRRFHKACHLVHSFTDAVIQDRRR 281

  Fly   256 ------ETVAVREKEHIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFFIAGFET 314
                  |...::.|...|..||:|:|:..|:      |:|   :.|:.|::.|:|..|...|.:|
Mouse   282 TLPSKHEDDVLKAKAKSKTLDFIDVLLLSKD------EDG---KELSDEDIRAEADTFMFEGHDT 337

  Fly   315 SSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECT---------KDLKYLNQVLDETL 370
            ::|.:.:.||.||::|:.|::.|.||:|::...:.. ..||:         ..|.:|...:.|:|
Mouse   338 TASGLSWILYNLARHPEYQERCRQEVQELLRDREST-EIECSCAVFLRDDLAQLPFLTMCIKESL 401

  Fly   371 RLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAG 435
            ||:..|..:.|...:..|:|  ...||..|...||...|.||:|:::|:|..:.|.||.||....
Mouse   402 RLHPPVTVISRRCTQDIVLP--DGRVIPKGVICIINIFATHHNPTVWPDPEVYDPFRFDPENIKD 464

  Fly   436 RPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGIY 500
            |..:|::||..|||||||..|...:.::.|||.:..|:.....|.|.    .....:|..:.|::
Mouse   465 RSPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRFRVLPDDKEPR----RKPELILRAEGGLW 525

  Fly   501 LKVE 504
            |:||
Mouse   526 LRVE 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	p450	39..503	CDD:278495	114/456 (25%)
Cyp4f15	NP_598888.1	p450	57..526	CDD:278495	113/454 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900