Protein Alignment Cyp6a8 and cyp4b1.3

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_002931492.1
• Gene: cyp4b1.3 / 100487918
• XenbaseID: XB-GENE-980014
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 543
• Identity: 144/543 - (26%)
• Similarity: 230/543 - (42%)
• Gaps: 94/543 - (17%)

  Fly     5 YILFQVAVALLAILT------YYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQDHY 63
            |...|.|..|..||.      .:|..|......:..|....|.:.||..:.:......:......
 Frog    19 YQFGQFAALLCLILLLLKACGLFIRWKSLKDALQNFPGPPKHWLYGNANQFRNDGTDMDRILLWA 83

  Fly    64 NKFRESKAPFVGFFFFQSPAAFVI-DLELAKQILIKDFSNFSNKGIFYNEKDDP----------- 116
            ||:.::...:||.||    |:.|| :.|.||...               .:.||
 Frog    84 NKYPKAFPLWVGQFF----ASLVITNPEYAKAAF---------------ARSDPKTPTGYDFLIP 129

  Fly   117 -ISAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVP---KNSVLEIRD 177
             |...|..|.|..|...|..|:..|....:| .|..::|.:.:.|  :.:.||   |...:|:..
 Frog   130 WIGKGLLVLSGDTWFQHRRLLTPGFHYDVLK-PYAKLISDSTKVM--LDKWVPFSNKGEPVELFH 191

  Fly   178 LVARFTVDVIGTCAFGIQCNSLRDEKAEF--LYFGKRSLVDKR------HGTLL-----NGFM-R 228
            .|:..|:|.|..|||....|...|....:  ..:....|...|      |..|:     :||: |
 Frog   192 HVSLMTLDSIMKCAFSYHSNCQTDNDNSYTKAVYDLSYLTHHRARTFPYHNNLIYYLSPHGFLFR 256

  Fly   229 SYPKLARKLGMVRTAPHIQEFYSRIVT------ETVAVREKEHIKRNDFMDMLIELKNQKEMTLE 287
            ...::|.:        |..:...:..|      |...|::|.|   .||:|:|:..::      |
 Frog   257 KACRIAHQ--------HTDKVIKQRKTLLQNKEEFEKVKQKRH---PDFLDILLCARD------E 304

  Fly   288 NGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFT 352
            ||   :||:.|::.|:...|...|.:|::|.:.:.||.:||.|:.|.|.|.|:.:|:.: .::|.
 Frog   305 NG---KGLSDEDLRAEVDTFMFEGHDTTASGISWILYCMAKYPEHQQKCREEIRDVLGE-KESFE 365

  Fly   353 YECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIY 417
            :|....:.|....:.|:||||..||.:.|...|........:  :.||..:.|....||.:|:::
 Frog   366 WEDLNKIPYTTMCIKESLRLYPPVPAVSRELNKPITFSDGRS--LPAGSVIFINIFCIHRNPTVW 428

  Fly   418 PEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFS-TCSKTP 481
            .:|..|.|.|||.|.|:.|.|.|::||..|||||||..|...:.::.:||.:..::.| ..||.|
 Frog   429 KDPEVFDPLRFSSENSSKRHSHAFVPFAAGPRNCIGQNFAMNELKVAVALTLNRYELSPDLSKAP 493

  Fly   482 NPLVYDPKSFVLGVKDGI--YLK 502
               :..|: .||..|:||  |||
 Frog   494 ---LKSPQ-LVLRSKNGIHVYLK 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	127/468 (27%)
cyp4b1.3	XP_002931492.1	CYP4B-like	76..510	CDD:410771	129/482 (27%)