Protein Alignment Cyp6a8 and LOC100487846

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: XP_017950484.2
• Gene: LOC100487846 / 100487846
• XenbaseID: XB-GENE-29078943
• Length: 512
• Species: Xenopus tropicalis
• Alignment Length: 493
• Identity: 144/493 - (29%)
• Similarity: 252/493 - (51%)
• Gaps: 46/493 - (9%)

  Fly    12 VALLAILTYYIHRKLTYFKRRG------IPFVAPHLIRGNMEELQKTKNIHEIFQDHYNKFRESK 70
            |.||.:|.||.......|||.|      |||:...|  ||...|.:..  .:.|:.:.|.:
 Frog    16 VLLLTLLAYYAIWPYRLFKRYGIPGPTPIPFIGTFL--GNRHGLMEFD--MKCFKKYGNVW---- 72

  Fly    71 APFVGFFFFQSPAAFVIDLELAKQILIKD-FSNFSNKGIFYNEKDDPISAHLFNLDGAQWRLLRN 134
                ||:....|...::|..:.|.|::|: ::||:|:..|  ....|:.:.:......||:.:|.
 Frog    73 ----GFYDGPQPVLAILDPVIIKSIMVKECYTNFTNRRDF--GLSGPLKSSVLMSKDEQWKRIRT 131

  Fly   135 KLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRDLVARFTVDVIGTCAFGIQCNSL 199
            .||.||||||:|.|:|.:.......:..:|:|:.....|:::.:...:::|.|.:.:|.:..:|:
 Frog   132 VLSPTFTSGKLKQMFPLMKHYGELLVKNIHKKIDNKEPLDMKSIFGSYSMDTILSTSFSVNVDSM 196

  Fly   200 RDEKAEFL----------YFGKRSLVDKRHGTLLNGFMRSYPKLARKLGMVRTAPHIQEFYSRIV 254
            .:....|:          :|....|:     |:|..|:..:   ..|:.....:....:|:...|
 Frog   197 NNPNDPFVTNARNLFTFSFFKPLFLI-----TILCPFLVPF---LDKMNFCFLSSKFLKFFKDAV 253

  Fly   255 TETVAVREK-EHIKRNDFMDMLIELKNQKEMTLENGDVVR--GLTMEEVLAQAFVFFIAGFETSS 316
            ......|:| .|:.|.||:.::::.::.:..::...:..|  .|:..|:|||:.:|.:||:||:|
 Frog   254 ASIKKKRQKGAHMDRVDFLQLMVDAQSNEGESVPEEEKHRHKELSDTEILAQSLIFIMAGYETTS 318

  Fly   317 STMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDR 381
            :|:.|..|.:|:.||:|.|:..|:..::...... ||:....::|::.|::|||||......:||
 Frog   319 TTLMFLTYNIARYPDVQRKLEEEINTLLPNKAPP-TYDALMKMEYMDMVINETLRLLPPAIRIDR 382

  Fly   382 MAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGD 446
            :..|...:.|   ..|.||..:::|..|:|.:|.|:|||.||:|||||.|....:....:||||.
 Frog   383 VCKKTMEING---VTIPAGVVIVVPLFALHLNPEIWPEPEEFQPERFSKENQKNQDPYNFLPFGV 444

  Fly   447 GPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPL 484
            |||||||:||..:..::.|.:|::|||..||..||.||
 Frog   445 GPRNCIGMRFALVNIKLALTILLQNFKLETCKDTPVPL 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	125/429 (29%)
LOC100487846	XP_017950484.2	cytochrome_P450	67..498	CDD:477761	126/438 (29%)