Protein Alignment Cyp6a8 and Cyp4a32

DIOPT Version :10

• Sequence 1: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Sequence 2: NP_001093651.1
• Gene: Cyp4a32 / 100040843
• MGIID: 3717148
• Length: 509
• Species: Mus musculus
• Alignment Length: 523
• Identity: 134/523 - (25%)
• Similarity: 238/523 - (45%)
• Gaps: 63/523 - (12%)

  Fly     9 QVA--VALLAILT----YYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIFQ--DHYNK 65
            |||  :.||.:|.    :|:|||......:..|....|...|: |:.:..:.:.|:..  :|:
Mouse    20 QVASVLGLLLLLVKAVQFYLHRKWLLKALQQFPSPPFHWFFGH-EQFKGEQELKEVVSCIEHF-- 81

  Fly    66 FRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQWR 130
                .:.|..:|:..:....|.|.:..|.||.:  |:....|| |......|...|..|:|..|.
Mouse    82 ----PSAFPCWFWGSNAYLTVYDPDYMKVILGR--SDPKANGI-YRLLAPWIGYGLLLLNGQPWF 139

  Fly   131 LLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEK----VPKNSVLEIRDLVARFTVDVIGTCA 191
            ..|..|:..|   ...::.|.|.::|:. :.:|.:|    ..::|.:||...::..|:|.:..||
Mouse   140 QHRRMLTPAF---HYDILKPYVKNMADS-IRLMLDKWERLAGQDSSIEIFQHISLMTLDTVMKCA 200

  Fly   192 FGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGF--------MRSYPKLAR---KLGMVRTAPH 245
            |..:.:...|...:........|.:..|..:.|.|        :.|..:||:   :|....|...
Mouse   201 FSHKGSVQVDGNYKTYLQAIGDLNNLFHSRVRNIFHQNDTIYRLSSNGRLAKQACQLAHDHTDGV 265

  Fly   246 IQEFYSRIVTETVAVREKEHIK---RNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVF 307
            |:....::..|    .|.|:||   |.||:|:|:..:      :||||   .::.:::.|:...|
Mouse   266 IKMRKDQLQDE----GELENIKKKRRLDFLDILLFAR------MENGD---SMSDKDLRAEVDTF 317

  Fly   308 FIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRL 372
            ...|.:|::|.:.:..|.||.:|:.|.:.|.||:.::.. ..:.|::....:.|....:.|.|||
Mouse   318 MFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLLGD-GSSITWDHLDQIPYTTMCIKEALRL 381

  Fly   373 YTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRP 437
            |..||.:.|..:.....|...:  :..|..|.:....:||:|.::|.|..|.|.||:|:  :.|.
Mouse   382 YPPVPGIVRELSTSVTFPDGRS--LPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPD--SPRH 442

  Fly   438 SVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFK-FSTCSKTPNPLVYDPKSFVLGVKDGIYL 501
            |.::|||..|.|||||.:|...:.::.:||.:.:|: ....::.|.||.    ..||..|:||||
Mouse   443 SHSFLPFSGGARNCIGKQFAMSELKVIVALTLLHFELLPDPTRVPEPLA----RIVLKSKNGIYL 503

  Fly   502 KVE 504
            .::
Mouse   504 HLK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	115/448 (26%)
Cyp4a32	NP_001093651.1	CYP4B-like	71..504	CDD:410771	119/467 (25%)