DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a21 and CYP97A3

DIOPT Version :9

Sequence 1:	NP_611003.2	Gene:	Cyp6a21 / 36665	FlyBaseID:	FBgn0033981	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_564384.1	Gene:	CYP97A3 / 840067	AraportID:	AT1G31800	Length:	595	Species:	Arabidopsis thaliana

Alignment Length:	513	Identity:	119/513 - (23%)
Similarity:	227/513 - (44%)	Gaps:	80/513 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LTALLALVGYLLMK--WRSTMRH-WQDLGIPC--------------EEPHI--LMGSMKGVRTAR 53
            |:|.:|...:.:.|  :.||::: ...:|||.              :.|.:  ..||::.||...
plant    63 LSARIASGAFTVRKSSFPSTVKNGLSKIGIPSNVLDFMFDWTGSDQDYPKVPEAKGSIQAVRNEA 127

  Fly    54 SF---NEIWTSYYNKFRGS-GPFAGFYWFRRPAVFVLETSLAKQILIKEFNKFTDRGFFHNPEDD 114
            .|   .|::.:|...||.: ||        :..:.|.:.|:||.|| |:..|...:|......|.
plant   128 FFIPLYELFLTYGGIFRLTFGP--------KSFLIVSDPSIAKHIL-KDNAKAYSKGILAEILDF 183

  Fly   115 PLSGQLFLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKVANEFTDVFGQNV----AKSPVVEVR 175
            .:...|...||:.||..|..:....   ..||: ..::.:..|.:|...|.:    .|...||:.
plant   184 VMGKGLIPADGEIWRRRRRAIVPAL---HQKYV-AAMISLFGEASDRLCQKLDAAALKGEEVEME 244

  Fly   176 ELLARFTTDVIGTCAFGIECSSLKDP----DAEFREMGRRSLTEQRLGPVGIGFVNSFPNLARRL 236
            .|.:|.|.|:||...|..:..||.:.    :|.:..:  |...::.:.|:.:..:..:.:::.|.
plant   245 SLFSRLTLDIIGKAVFNYDFDSLTNDTGVIEAVYTVL--REAEDRSVSPIPVWDIPIWKDISPRQ 307

  Fly   237 HMKMTAEPIERFFMRIVRETV--------AFREQNNIRRNDFMDQLIDLKNKPLM--VSQSGESV 291
            ....|:       ::::.:|:        ...|:..::   |.::.::.::..::  :..||:.|
plant   308 RKVATS-------LKLINDTLDDLIATCKRMVEEEELQ---FHEEYMNERDPSILHFLLASGDDV 362

  Fly   292 NLTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGEL--NYESM 354
              :.:::.........||.|||:..:.:..|.|.....:..::::|...||    |:.  ..:.|
plant   363 --SSKQLRDDLMTMLIAGHETSAAVLTWTFYLLTTEPSVVAKLQEEVDSVI----GDRFPTIQDM 421

  Fly   355 KDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPN 419
            |.|.|..:|::|:||||...|||.|..: |.::.|  :|.||:|..:.|....:||....:.:..
plant   422 KKLKYTTRVMNESLRLYPQPPVLIRRSI-DNDILG--EYPIKRGEDIFISVWNLHRSPLHWDDAE 483

  Fly   420 TFNPDNF---SPERVKERDSVEWLPFGDGPRNCIGMRFGQMQARIGLALLIKDFKFSV 474
            .|||:.:   .|...:...:..:||||.|||.|||..|...:..:.:|:||:.|.|.:
plant   484 KFNPERWPLDGPNPNETNQNFSYLPFGGGPRKCIGDMFASFENVVAIAMLIRRFNFQI 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	111/483 (23%)
CYP97A3	NP_564384.1	PLN02738	1..595	CDD:215393	119/513 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900