DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a21 and CYP705A12

DIOPT Version :9

Sequence 1:	NP_611003.2	Gene:	Cyp6a21 / 36665	FlyBaseID:	FBgn0033981	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_199072.1	Gene:	CYP705A12 / 834265	AraportID:	AT5G42580	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	545	Identity:	116/545 - (21%)
Similarity:	218/545 - (40%)	Gaps:	120/545 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SVGTVLLTALLALVGYLLMKWRSTMRHWQDLGIPCEEP---------HILMGSMKGVRTARSFNE 57
            ::...:|..|.:.:.|.|.     .:..:...:|...|         |:|..|:    ..:||.:
plant    11 NISIFILLCLFSFLCYALF-----FKKPKGFDLPPSPPSLPIIGHLHHLLSSSL----PHKSFQK 66

  Fly    58 IWTSYYNKFRGSGPFAGFYWFRRPAVFVLETSLAKQI--------------LIKEFNKFTDRGFF 108
            :...|       ||......|..|.|.|...|:|.::              :.|:...|...||.
plant    67 LSFKY-------GPLLHLRIFNFPMVLVSSASMAYEVFRTNDVNVSYRFVPVNKDSLVFGSSGFV 124

  Fly   109 HNPEDDPLSGQLFLLDGQKWRTMRNKLSSTFTSGKMKYMFPTVVKV-----ANEF----TDVFGQ 164
            ..|.            |..|:.|: ||.||      |.:.|..:::     |.|.    .|:.|:
plant   125 TAPY------------GDYWKFMK-KLIST------KLLRPHALELSKGNRAEELRRFCLDLQGK 170

  Fly   165 NVAKSPVVEVRELLARFTTDVIGTCAFGIECSSLKDPDAEFREMGRRSLTEQRLGPVGIGFVNSF 229
             ..|...||:.::..:.|.::|...:.|..||.........||:..:|.        .:.....|
plant   171 -ARKKESVEIGKVALKLTNNIICRMSMGRSCSEKNGVAERARELVNKSF--------ALSVKLFF 226

  Fly   230 PNLARRLHMKMTAEPIERFFMRIVRETVAFREQN--NIRRNDFMDQLID-LKNKPLMVSQSGESV 291
            .|:.|:..|.::.| .:.|..||:.|    .|:|  ..:..|.:|.|:: .:|:......:.:.:
plant   227 SNMFRKDIMGVSRE-FDEFLERILVE----HEENLEGDQDRDMIDHLLEAYRNEEAEYKITRKQI 286

  Fly   292 NLTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQDIQNRVRKECQEVIEKCNGE--LNYESM 354
            ...|.||       |..|.::|:.|:.:.:.|:..|..:..::|.|...|:   .|:  :....:
plant   287 KSLIVEI-------FLGGTDSSAQTIQWTMAEILNNPGVLEKLRAEIDSVV---GGKRLIQESDL 341

  Fly   355 KDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHPKYVIKKGMPVLIPCGAMHRDEKLYANPN 419
            .:|.||..||.|.|||:...|||.|...|..||   .::.:.:...:::...|::||...:.:|:
plant   342 PNLPYLQAVVKEGLRLHPSAPVLLRVFGESCEV---KEFYVPEKTTLVVNLYAVNRDPDSWEDPD 403

  Fly   420 TFNPDNF-------SPERVKERDSVEWLPFGDGPRNCIGMRFGQ--MQARIGLALLIKDFKFSVC 475
            .|.|:.|       ..|:::|: :|:::.||.|.|.|..::...  |:..||..:...|::..
plant   404 MFKPERFLVSSISGDEEKIREQ-AVKYVTFGGGRRTCPAVKLAHIFMETAIGAMVQCFDWRIK-- 465

  Fly   476 EKTTIPMTYNKEMFLIASNSGIYLK 500
                     .:::::..:.||:.||
plant   466 ---------GEKVYMEEAVSGLSLK 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a21	NP_611003.2	p450	35..499	CDD:278495	110/509 (22%)
CYP705A12	NP_199072.1	CYP93	72..490	CDD:410748	104/468 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010